Visual pathology reports for communication of final margin status in laryngeal cancer surgery

Background: Positive margins are frequently observed in total laryngectomy (TL) specimens. Effective communication of margin sampling sites and final margin status between surgeons and pathologists is crucial. In this study, we evaluate the utility of multimedia visual pathology reports to facilitat...

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Main Authors: Marina Aweeda, Carly Fassler, Alexander N. Perez, Alexis Miller, Kavita Prasad, Kayvon F. Sharif, James S. Lewis, Jr, Kim A. Ely, Mitra Mehrad, Sarah L. Rohde, Alexander J. Langerman, Kyle Mannion, Robert J. Sinard, James L. Netterville, Eben L. Rosenthal, Michael C. Topf
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:Journal of Pathology Informatics
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Online Access:http://www.sciencedirect.com/science/article/pii/S2153353924000439
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author Marina Aweeda
Carly Fassler
Alexander N. Perez
Alexis Miller
Kavita Prasad
Kayvon F. Sharif
James S. Lewis, Jr
Kim A. Ely
Mitra Mehrad
Sarah L. Rohde
Alexander J. Langerman
Kyle Mannion
Robert J. Sinard
James L. Netterville
Eben L. Rosenthal
Michael C. Topf
author_facet Marina Aweeda
Carly Fassler
Alexander N. Perez
Alexis Miller
Kavita Prasad
Kayvon F. Sharif
James S. Lewis, Jr
Kim A. Ely
Mitra Mehrad
Sarah L. Rohde
Alexander J. Langerman
Kyle Mannion
Robert J. Sinard
James L. Netterville
Eben L. Rosenthal
Michael C. Topf
author_sort Marina Aweeda
collection DOAJ
description Background: Positive margins are frequently observed in total laryngectomy (TL) specimens. Effective communication of margin sampling sites and final margin status between surgeons and pathologists is crucial. In this study, we evaluate the utility of multimedia visual pathology reports to facilitate interdisciplinary discussion of margin status in laryngeal cancer surgery. Methods: Ex vivo laryngeal cancer surgical specimens were three-dimensional (3D) scanned before standard of care pathological analysis. Using computer-aided design software, the 3D model was annotated to reflect inking, sectioning, and margin sampling sites, generating a visual pathology report. These reports were distributed to head and neck surgeons and pathologists postoperatively. Results: Fifteen laryngeal cancer surgical specimens were 3D scanned and virtually annotated from January 2022 to December 2023. Most specimens (73.3%) were squamous cell carcinomas (SCCs). Among the cases, 26.7% had final positive surgical margins, whereas 13.3% had close margins, defined as <5 mm. The visual pathology report demonstrated sites of close or positive margins on the 3D specimens and was used to facilitate postoperative communication between surgeons and pathologists in 85.7% of these cases. Visual pathology reports were presented in multidisciplinary tumor board discussions (20%), email correspondences (13.3%), and teleconferences (6.7%), and were referenced in the final written pathology reports (26.7%). Conclusions: 3D scanning and virtual annotation of laryngeal cancer specimens for the creation of visual pathology reports is an innovative approach for postoperative pathology documentation, margin analysis, and surgeon–pathologist communication.
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spelling doaj-art-c2f9e7eeee744d11b9317dd1d5fcd5f42025-08-20T02:38:05ZengElsevierJournal of Pathology Informatics2153-35392024-12-011510040410.1016/j.jpi.2024.100404Visual pathology reports for communication of final margin status in laryngeal cancer surgeryMarina Aweeda0Carly Fassler1Alexander N. Perez2Alexis Miller3Kavita Prasad4Kayvon F. Sharif5James S. Lewis, Jr6Kim A. Ely7Mitra Mehrad8Sarah L. Rohde9Alexander J. Langerman10Kyle Mannion11Robert J. Sinard12James L. Netterville13Eben L. Rosenthal14Michael C. Topf15Department of Otolaryngology – Head and Neck Surgery, Vanderbilt University Medical Center, Nashville, TN, USADepartment of Otolaryngology – Head and Neck Surgery, Vanderbilt University Medical Center, Nashville, TN, USADepartment of Pathology, Microbiology and Immunology, Vanderbilt University Medical Center, Nashville, TN, USADepartment of Otolaryngology – Head and Neck Surgery, Vanderbilt University Medical Center, Nashville, TN, USADepartment of Otolaryngology – Head and Neck Surgery, Vanderbilt University Medical Center, Nashville, TN, USADepartment of Otolaryngology – Head and Neck Surgery, Mayo Clinic, Rochester, MN, USADepartment of Otolaryngology – Head and Neck Surgery, Vanderbilt University Medical Center, Nashville, TN, USA; Department of Pathology, Microbiology and Immunology, Vanderbilt University Medical Center, Nashville, TN, USA; Department of Laboratory Medicine and Pathology, Mayo Clinic, Phoenix, AZ, USADepartment of Pathology, Microbiology and Immunology, Vanderbilt University Medical Center, Nashville, TN, USADepartment of Pathology, Microbiology and Immunology, Vanderbilt University Medical Center, Nashville, TN, USADepartment of Otolaryngology – Head and Neck Surgery, Vanderbilt University Medical Center, Nashville, TN, USADepartment of Otolaryngology – Head and Neck Surgery, Vanderbilt University Medical Center, Nashville, TN, USADepartment of Otolaryngology – Head and Neck Surgery, Vanderbilt University Medical Center, Nashville, TN, USADepartment of Otolaryngology – Head and Neck Surgery, Vanderbilt University Medical Center, Nashville, TN, USADepartment of Otolaryngology – Head and Neck Surgery, Vanderbilt University Medical Center, Nashville, TN, USADepartment of Otolaryngology – Head and Neck Surgery, Vanderbilt University Medical Center, Nashville, TN, USADepartment of Otolaryngology – Head and Neck Surgery, Vanderbilt University Medical Center, Nashville, TN, USA; School of Engineering, Vanderbilt University, Nashville, TN, USA; Corresponding author at: Department of Otolaryngology—Head and Neck Surgery, Vanderbilt University Medical Center, 1215 21st Ave. S. Suite 7209, Nashville, TN 37232, USA.Background: Positive margins are frequently observed in total laryngectomy (TL) specimens. Effective communication of margin sampling sites and final margin status between surgeons and pathologists is crucial. In this study, we evaluate the utility of multimedia visual pathology reports to facilitate interdisciplinary discussion of margin status in laryngeal cancer surgery. Methods: Ex vivo laryngeal cancer surgical specimens were three-dimensional (3D) scanned before standard of care pathological analysis. Using computer-aided design software, the 3D model was annotated to reflect inking, sectioning, and margin sampling sites, generating a visual pathology report. These reports were distributed to head and neck surgeons and pathologists postoperatively. Results: Fifteen laryngeal cancer surgical specimens were 3D scanned and virtually annotated from January 2022 to December 2023. Most specimens (73.3%) were squamous cell carcinomas (SCCs). Among the cases, 26.7% had final positive surgical margins, whereas 13.3% had close margins, defined as <5 mm. The visual pathology report demonstrated sites of close or positive margins on the 3D specimens and was used to facilitate postoperative communication between surgeons and pathologists in 85.7% of these cases. Visual pathology reports were presented in multidisciplinary tumor board discussions (20%), email correspondences (13.3%), and teleconferences (6.7%), and were referenced in the final written pathology reports (26.7%). Conclusions: 3D scanning and virtual annotation of laryngeal cancer specimens for the creation of visual pathology reports is an innovative approach for postoperative pathology documentation, margin analysis, and surgeon–pathologist communication.http://www.sciencedirect.com/science/article/pii/S2153353924000439Surgical pathology3D scanningHead and neck cancerSurgical margins
spellingShingle Marina Aweeda
Carly Fassler
Alexander N. Perez
Alexis Miller
Kavita Prasad
Kayvon F. Sharif
James S. Lewis, Jr
Kim A. Ely
Mitra Mehrad
Sarah L. Rohde
Alexander J. Langerman
Kyle Mannion
Robert J. Sinard
James L. Netterville
Eben L. Rosenthal
Michael C. Topf
Visual pathology reports for communication of final margin status in laryngeal cancer surgery
Journal of Pathology Informatics
Surgical pathology
3D scanning
Head and neck cancer
Surgical margins
title Visual pathology reports for communication of final margin status in laryngeal cancer surgery
title_full Visual pathology reports for communication of final margin status in laryngeal cancer surgery
title_fullStr Visual pathology reports for communication of final margin status in laryngeal cancer surgery
title_full_unstemmed Visual pathology reports for communication of final margin status in laryngeal cancer surgery
title_short Visual pathology reports for communication of final margin status in laryngeal cancer surgery
title_sort visual pathology reports for communication of final margin status in laryngeal cancer surgery
topic Surgical pathology
3D scanning
Head and neck cancer
Surgical margins
url http://www.sciencedirect.com/science/article/pii/S2153353924000439
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