Diagnosis of Thymic Clear Cell Carcinoma by Cytology

Clear cell carcinoma of the thymus is a rare tumor. Few cases of clear-cell carcinoma of thymus have been documented (Truong et al., 1990 and Wolfe III et al., 1983). All these cases were diagnosed by histopathological examination of the tissue. Diagnosis of thymic clear cell carcinoma on cytology i...

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Main Authors: Seema A. Lale, Patricia G. Tiscornia-Wasserman, Mohamed Aziz
Format: Article
Language:English
Published: Wiley 2013-01-01
Series:Case Reports in Pathology
Online Access:http://dx.doi.org/10.1155/2013/617810
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author Seema A. Lale
Patricia G. Tiscornia-Wasserman
Mohamed Aziz
author_facet Seema A. Lale
Patricia G. Tiscornia-Wasserman
Mohamed Aziz
author_sort Seema A. Lale
collection DOAJ
description Clear cell carcinoma of the thymus is a rare tumor. Few cases of clear-cell carcinoma of thymus have been documented (Truong et al., 1990 and Wolfe III et al., 1983). All these cases were diagnosed by histopathological examination of the tissue. Diagnosis of thymic clear cell carcinoma on cytology is extremely challenging. Here we report the first case of thymic clear cell carcinoma diagnosed by cytological examination of the pericardial fluid with the help of immunocytochemistry. Differential diagnosis included adenocarcinoma, mesothelioma, and thymic clear cell carcinoma. Thymic carcinoma with clear cell features has an aggressive clinical behavior including our case, where it was already metastasized at the time of presentation.
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series Case Reports in Pathology
spelling doaj-art-c2f5453e5f024dcbbe3db96fc547c67d2025-02-03T01:23:05ZengWileyCase Reports in Pathology2090-67812090-679X2013-01-01201310.1155/2013/617810617810Diagnosis of Thymic Clear Cell Carcinoma by CytologySeema A. Lale0Patricia G. Tiscornia-Wasserman1Mohamed Aziz2Mercy Hospital, 800 Myrtle Street, Independence, KS 67301, USACytopathology, Columbia University Medical Center, 630 West 168th Street, PH15-1586, New York, NY 10032, USACytopathology, Hofstra North Shore-LIJ School of Medicine and at New York Medical College, 6 Ohio drive, Lake Success, NY 11042, USAClear cell carcinoma of the thymus is a rare tumor. Few cases of clear-cell carcinoma of thymus have been documented (Truong et al., 1990 and Wolfe III et al., 1983). All these cases were diagnosed by histopathological examination of the tissue. Diagnosis of thymic clear cell carcinoma on cytology is extremely challenging. Here we report the first case of thymic clear cell carcinoma diagnosed by cytological examination of the pericardial fluid with the help of immunocytochemistry. Differential diagnosis included adenocarcinoma, mesothelioma, and thymic clear cell carcinoma. Thymic carcinoma with clear cell features has an aggressive clinical behavior including our case, where it was already metastasized at the time of presentation.http://dx.doi.org/10.1155/2013/617810
spellingShingle Seema A. Lale
Patricia G. Tiscornia-Wasserman
Mohamed Aziz
Diagnosis of Thymic Clear Cell Carcinoma by Cytology
Case Reports in Pathology
title Diagnosis of Thymic Clear Cell Carcinoma by Cytology
title_full Diagnosis of Thymic Clear Cell Carcinoma by Cytology
title_fullStr Diagnosis of Thymic Clear Cell Carcinoma by Cytology
title_full_unstemmed Diagnosis of Thymic Clear Cell Carcinoma by Cytology
title_short Diagnosis of Thymic Clear Cell Carcinoma by Cytology
title_sort diagnosis of thymic clear cell carcinoma by cytology
url http://dx.doi.org/10.1155/2013/617810
work_keys_str_mv AT seemaalale diagnosisofthymicclearcellcarcinomabycytology
AT patriciagtiscorniawasserman diagnosisofthymicclearcellcarcinomabycytology
AT mohamedaziz diagnosisofthymicclearcellcarcinomabycytology