Production and characterisation of a SARS-CoV-2 S-protein RBD homodimer with increased avidity for specific antibodies

Production and characterisation of a SARS-CoV-2 S-protein RBD homodimer with increased avidity for specific antibodies

Monitoring of the proportion of immune individuals and the effectiveness of vaccination in a population involves evaluation of several important parameters, including the level of virus-neutralising antibodies. In order to combat the COVID-19 pandemic, it is essential to develop approaches to detect...

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Bibliographic Details
Main Authors: A. A. Derkaev, E. I. Ryabova, V. V. Prokofiev, I. A. Favorskaya, D. M. Grousova, I. B. Esmagambetov, I. V. Dolzhikova, D. V. Shcheblyakov
Format: Article
Language:Russian
Published: Ministry of Health of the Russian Federation. Federal State Budgetary Institution «Scientific Centre for Expert Evaluation of Medicinal Products» 2023-04-01
Series:Биопрепараты: Профилактика, диагностика, лечение
Subjects:
recombinant protein
coronavirus infection
receptor-binding domain
sars-cov-2
avidity
Online Access:https://www.biopreparations.ru/jour/article/view/450
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