Expert Opinion on the Diagnosis and Management of Male Hypogonadism in India
Male hypogonadism (MH) is a clinical and biochemical syndrome caused by inadequate synthesis of testosterone. Untreated MH can result in long-term effects, including metabolic, musculoskeletal, mood-related, and reproductive dysfunction. Among Indian men above 40 years of age, the prevalence of MH i...
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| Format: | Article |
| Language: | English |
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Wiley
2023-01-01
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| Series: | International Journal of Endocrinology |
| Online Access: | http://dx.doi.org/10.1155/2023/4408697 |
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| author | Sanjay Kalra Jubbin Jacob A. G. Unnikrishnan Ganapathi Bantwal Abhay Sahoo Rakesh Sahay Sushil Jindal Madhu Sudan Agrawal Nitin Kapoor Banshi Saboo Mangesh Tiwaskar Kapil Kochhar |
| author_facet | Sanjay Kalra Jubbin Jacob A. G. Unnikrishnan Ganapathi Bantwal Abhay Sahoo Rakesh Sahay Sushil Jindal Madhu Sudan Agrawal Nitin Kapoor Banshi Saboo Mangesh Tiwaskar Kapil Kochhar |
| author_sort | Sanjay Kalra |
| collection | DOAJ |
| description | Male hypogonadism (MH) is a clinical and biochemical syndrome caused by inadequate synthesis of testosterone. Untreated MH can result in long-term effects, including metabolic, musculoskeletal, mood-related, and reproductive dysfunction. Among Indian men above 40 years of age, the prevalence of MH is 20%–29%. Among men with type 2 diabetes mellitus, 20.7% are found to have hypogonadism. However, due to suboptimal patient-physician communication, MH remains heavily underdiagnosed. For patients with confirmed hypogonadism (either primary or secondary testicular failure), testosterone replacement therapy (TRT) is recommended. Although various formulations exist, optimal TRT remains a considerable challenge as patients often need individually tailored therapeutic strategies. Other challenges include the absence of standardized guidelines on MH for the Indian population, inadequate physician education on MH diagnosis and referral to endocrinologists, and a lack of patient awareness of the long-term effects of MH in relation to comorbidities. Five nationwide advisory board meetings were convened to garner expert opinions on diagnosis, investigations, and available treatment options for MH, as well as the need for a person-centered approach. Experts’ opinions have been formulated into a consensus document with the aim of improving the screening, diagnosis, and therapy of men living with hypogonadism. |
| format | Article |
| id | doaj-art-c2eb98e9150c4b92aa4c63863167d794 |
| institution | DOAJ |
| issn | 1687-8345 |
| language | English |
| publishDate | 2023-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | International Journal of Endocrinology |
| spelling | doaj-art-c2eb98e9150c4b92aa4c63863167d7942025-08-20T03:04:51ZengWileyInternational Journal of Endocrinology1687-83452023-01-01202310.1155/2023/4408697Expert Opinion on the Diagnosis and Management of Male Hypogonadism in IndiaSanjay Kalra0Jubbin Jacob1A. G. Unnikrishnan2Ganapathi Bantwal3Abhay Sahoo4Rakesh Sahay5Sushil Jindal6Madhu Sudan Agrawal7Nitin Kapoor8Banshi Saboo9Mangesh Tiwaskar10Kapil Kochhar11Department of EndocrinologyDepartment of EndocrinologyChellaram Diabetes InstituteDepartment of EndocrinologyDepartment of EndocrinologyDepartment of EndocrinologyPeople’s Medical College and Research CentreDepartment of UrologyBaker Heart and Diabetes InstituteDepartment of MedicineDepartment of MedicineAndrology ClinicMale hypogonadism (MH) is a clinical and biochemical syndrome caused by inadequate synthesis of testosterone. Untreated MH can result in long-term effects, including metabolic, musculoskeletal, mood-related, and reproductive dysfunction. Among Indian men above 40 years of age, the prevalence of MH is 20%–29%. Among men with type 2 diabetes mellitus, 20.7% are found to have hypogonadism. However, due to suboptimal patient-physician communication, MH remains heavily underdiagnosed. For patients with confirmed hypogonadism (either primary or secondary testicular failure), testosterone replacement therapy (TRT) is recommended. Although various formulations exist, optimal TRT remains a considerable challenge as patients often need individually tailored therapeutic strategies. Other challenges include the absence of standardized guidelines on MH for the Indian population, inadequate physician education on MH diagnosis and referral to endocrinologists, and a lack of patient awareness of the long-term effects of MH in relation to comorbidities. Five nationwide advisory board meetings were convened to garner expert opinions on diagnosis, investigations, and available treatment options for MH, as well as the need for a person-centered approach. Experts’ opinions have been formulated into a consensus document with the aim of improving the screening, diagnosis, and therapy of men living with hypogonadism.http://dx.doi.org/10.1155/2023/4408697 |
| spellingShingle | Sanjay Kalra Jubbin Jacob A. G. Unnikrishnan Ganapathi Bantwal Abhay Sahoo Rakesh Sahay Sushil Jindal Madhu Sudan Agrawal Nitin Kapoor Banshi Saboo Mangesh Tiwaskar Kapil Kochhar Expert Opinion on the Diagnosis and Management of Male Hypogonadism in India International Journal of Endocrinology |
| title | Expert Opinion on the Diagnosis and Management of Male Hypogonadism in India |
| title_full | Expert Opinion on the Diagnosis and Management of Male Hypogonadism in India |
| title_fullStr | Expert Opinion on the Diagnosis and Management of Male Hypogonadism in India |
| title_full_unstemmed | Expert Opinion on the Diagnosis and Management of Male Hypogonadism in India |
| title_short | Expert Opinion on the Diagnosis and Management of Male Hypogonadism in India |
| title_sort | expert opinion on the diagnosis and management of male hypogonadism in india |
| url | http://dx.doi.org/10.1155/2023/4408697 |
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