Osteoarthritis-related knee pain: MRI-guided focused ultrasound ablation treatment
Objective: Osteoarthritis of the knee is a common cause of pain, functional disability, and reduced quality of life in the elderly. Despite its prevalence, there are limited currently available noninvasive treatment options. MRI-guided focused ultrasound (MRgFUS) is a noninvasive thermal ablation me...
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Taylor & Francis Group
2025-12-01
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| Series: | International Journal of Hyperthermia |
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| Online Access: | https://www.tandfonline.com/doi/10.1080/02656736.2025.2451686 |
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| author | Christin A. Tiegs-Heiden Zaiyang Long Aiming Lu Krzysztof R. Gorny Gina K. Hesley |
| author_facet | Christin A. Tiegs-Heiden Zaiyang Long Aiming Lu Krzysztof R. Gorny Gina K. Hesley |
| author_sort | Christin A. Tiegs-Heiden |
| collection | DOAJ |
| description | Objective: Osteoarthritis of the knee is a common cause of pain, functional disability, and reduced quality of life in the elderly. Despite its prevalence, there are limited currently available noninvasive treatment options. MRI-guided focused ultrasound (MRgFUS) is a noninvasive thermal ablation method which is used in a spectrum of musculoskeletal conditions. It is FDA approved for the treatment of painful bone metastases and osteoid osteoma and has been considered for the treatment of other painful conditions such as osteoarthritis. The purpose of this case report is to describe the use of MRgFUS for the treatment of osteoarthritic knee pain in an active 72-year-old male.Method: The patient suffered significant limitations due to lateral knee pain with jogging and walking down the stairs. MRgFUS ablation treatment was performed to the lateral knee, targeting the periosteum in the patients’ area of pain.Results: Following treatment, the patient experienced considerable reduction in his activity limiting symptoms with a duration of at least 6 months.Conclusions: It is important for radiologists to be aware of MRgFUS as an innovative ablation modality. Similar pain reduction was observed in two small series of MRgFUS treatment of knee pain from Japan. MRgFUS appears promising as a safe, noninvasive treatment option for temporary relief of knee pain. This may be particularly valuable for patients who are unwilling or unable to undergo total knee arthroplasty. Future study is needed to assess the efficacy and safety of this treatment in a larger population. |
| format | Article |
| id | doaj-art-c2e455efe5ff4c5780f8cfafa7a6ec87 |
| institution | Kabale University |
| issn | 0265-6736 1464-5157 |
| language | English |
| publishDate | 2025-12-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | International Journal of Hyperthermia |
| spelling | doaj-art-c2e455efe5ff4c5780f8cfafa7a6ec872025-01-20T01:07:41ZengTaylor & Francis GroupInternational Journal of Hyperthermia0265-67361464-51572025-12-0142110.1080/02656736.2025.2451686Osteoarthritis-related knee pain: MRI-guided focused ultrasound ablation treatmentChristin A. Tiegs-Heiden0Zaiyang Long1Aiming Lu2Krzysztof R. Gorny3Gina K. Hesley4Department of Radiology, Mayo Clinic, Rochester, MN, USADepartment of Radiology, Mayo Clinic, Rochester, MN, USADepartment of Radiology, Mayo Clinic, Rochester, MN, USADepartment of Radiology, Mayo Clinic, Rochester, MN, USADepartment of Radiology, Mayo Clinic, Rochester, MN, USAObjective: Osteoarthritis of the knee is a common cause of pain, functional disability, and reduced quality of life in the elderly. Despite its prevalence, there are limited currently available noninvasive treatment options. MRI-guided focused ultrasound (MRgFUS) is a noninvasive thermal ablation method which is used in a spectrum of musculoskeletal conditions. It is FDA approved for the treatment of painful bone metastases and osteoid osteoma and has been considered for the treatment of other painful conditions such as osteoarthritis. The purpose of this case report is to describe the use of MRgFUS for the treatment of osteoarthritic knee pain in an active 72-year-old male.Method: The patient suffered significant limitations due to lateral knee pain with jogging and walking down the stairs. MRgFUS ablation treatment was performed to the lateral knee, targeting the periosteum in the patients’ area of pain.Results: Following treatment, the patient experienced considerable reduction in his activity limiting symptoms with a duration of at least 6 months.Conclusions: It is important for radiologists to be aware of MRgFUS as an innovative ablation modality. Similar pain reduction was observed in two small series of MRgFUS treatment of knee pain from Japan. MRgFUS appears promising as a safe, noninvasive treatment option for temporary relief of knee pain. This may be particularly valuable for patients who are unwilling or unable to undergo total knee arthroplasty. Future study is needed to assess the efficacy and safety of this treatment in a larger population.https://www.tandfonline.com/doi/10.1080/02656736.2025.2451686MRI-guided focused ultrasoundkneeosteoarthritisHIFUthermal ablation |
| spellingShingle | Christin A. Tiegs-Heiden Zaiyang Long Aiming Lu Krzysztof R. Gorny Gina K. Hesley Osteoarthritis-related knee pain: MRI-guided focused ultrasound ablation treatment International Journal of Hyperthermia MRI-guided focused ultrasound knee osteoarthritis HIFU thermal ablation |
| title | Osteoarthritis-related knee pain: MRI-guided focused ultrasound ablation treatment |
| title_full | Osteoarthritis-related knee pain: MRI-guided focused ultrasound ablation treatment |
| title_fullStr | Osteoarthritis-related knee pain: MRI-guided focused ultrasound ablation treatment |
| title_full_unstemmed | Osteoarthritis-related knee pain: MRI-guided focused ultrasound ablation treatment |
| title_short | Osteoarthritis-related knee pain: MRI-guided focused ultrasound ablation treatment |
| title_sort | osteoarthritis related knee pain mri guided focused ultrasound ablation treatment |
| topic | MRI-guided focused ultrasound knee osteoarthritis HIFU thermal ablation |
| url | https://www.tandfonline.com/doi/10.1080/02656736.2025.2451686 |
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