Microfluidic isolation and release of live disseminated breast tumor cells in bone marrow.

Breast cancer represents a significant therapeutic challenge due to its aggressive nature and resistance to treatment. A major cause of treatment failure in breast cancer is the presence of rare, low-proliferative disseminated tumor cells (DTCs) in distant organs including the bone marrow. This stud...

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Bibliographic Details
Main Authors: Minh-Chau N Le, Dongjiang Chen, Kierstin A Smith, David D Tran, Z Hugh Fan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0319392
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