Evaluation of ctDNA-guided adjuvant therapy de-escalation in head and neck squamous cell carcinoma: a comparative cohort study

Evaluation of ctDNA-guided adjuvant therapy de-escalation in head and neck squamous cell carcinoma: a comparative cohort study

BackgroundWhile circulating tumor DNA (ctDNA) assessment after surgery has emerged as a promising biomarker for minimal residual disease detection in solid tumors, its clinical utility for guiding the selection between postoperative radiotherapy (PORT) and chemoradiotherapy (POCRT) in head and neck...

Full description

Saved in:
Bibliographic Details
Main Authors: Xu Zhang, Qigen Fang, Junhui Yuan, Liyuan Dai, Ruihua Luo, Tao Huang, Yinfei Wu
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-08-01
Series:Frontiers in Immunology
Subjects:
head and neck squamous cell carcinoma
CtDNA
neoadjuvant chemoimmunotherapy
adjuvant chemotherapy
pathologic complete response
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1576042/full
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items

Similar Items