Nonserogroup-1 Legionella pneumophila Pneumonia: Navigating Diagnostic Challenges

A 59-year-old woman with newly diagnosed immune thrombocytopenia treated with steroids and rituximab presented with a cavitary lung lesion. Extensive work-up, including bronchoalveolar lavage and transthoracic lung biopsy, were unrevealing. Molecular testing on lung tissue ultimately diagnosed nonse...

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Main Authors: Lara K. Rotter, Julian A. Villalba, Claressa E. Lucas, Melisa J. Willby, Marwan M. Azar
Format: Article
Language:English
Published: American College of Physicians 2025-01-01
Series:Annals of Internal Medicine: Clinical Cases
Online Access:https://www.acpjournals.org/doi/10.7326/aimcc.2024.0480
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author Lara K. Rotter
Julian A. Villalba
Claressa E. Lucas
Melisa J. Willby
Marwan M. Azar
author_facet Lara K. Rotter
Julian A. Villalba
Claressa E. Lucas
Melisa J. Willby
Marwan M. Azar
author_sort Lara K. Rotter
collection DOAJ
description A 59-year-old woman with newly diagnosed immune thrombocytopenia treated with steroids and rituximab presented with a cavitary lung lesion. Extensive work-up, including bronchoalveolar lavage and transthoracic lung biopsy, were unrevealing. Molecular testing on lung tissue ultimately diagnosed nonserogroup-1 Legionella pneumophila, underscoring the utility of advanced diagnostics in clinical conundrums.
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institution OA Journals
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publishDate 2025-01-01
publisher American College of Physicians
record_format Article
series Annals of Internal Medicine: Clinical Cases
spelling doaj-art-c2d5a9f9e1ba4a658afadccacbebe7512025-08-20T02:11:54ZengAmerican College of PhysiciansAnnals of Internal Medicine: Clinical Cases2767-76642025-01-014110.7326/aimcc.2024.0480Nonserogroup-1 Legionella pneumophila Pneumonia: Navigating Diagnostic ChallengesLara K. Rotter0Julian A. Villalba1Claressa E. Lucas2Melisa J. Willby3Marwan M. Azar41Department of Internal Medicine, Yale School of Medicine, New Haven, Connecticut3Infectious Diseases Pathology Branch, Division of High Consequence Pathogens and Pathology, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia4Division of Bacterial Diseases, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia4Division of Bacterial Diseases, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia1Department of Internal Medicine, Yale School of Medicine, New Haven, ConnecticutA 59-year-old woman with newly diagnosed immune thrombocytopenia treated with steroids and rituximab presented with a cavitary lung lesion. Extensive work-up, including bronchoalveolar lavage and transthoracic lung biopsy, were unrevealing. Molecular testing on lung tissue ultimately diagnosed nonserogroup-1 Legionella pneumophila, underscoring the utility of advanced diagnostics in clinical conundrums.https://www.acpjournals.org/doi/10.7326/aimcc.2024.0480
spellingShingle Lara K. Rotter
Julian A. Villalba
Claressa E. Lucas
Melisa J. Willby
Marwan M. Azar
Nonserogroup-1 Legionella pneumophila Pneumonia: Navigating Diagnostic Challenges
Annals of Internal Medicine: Clinical Cases
title Nonserogroup-1 Legionella pneumophila Pneumonia: Navigating Diagnostic Challenges
title_full Nonserogroup-1 Legionella pneumophila Pneumonia: Navigating Diagnostic Challenges
title_fullStr Nonserogroup-1 Legionella pneumophila Pneumonia: Navigating Diagnostic Challenges
title_full_unstemmed Nonserogroup-1 Legionella pneumophila Pneumonia: Navigating Diagnostic Challenges
title_short Nonserogroup-1 Legionella pneumophila Pneumonia: Navigating Diagnostic Challenges
title_sort nonserogroup 1 legionella pneumophila pneumonia navigating diagnostic challenges
url https://www.acpjournals.org/doi/10.7326/aimcc.2024.0480
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