Caveolin-1/PPARα axis suppresses T follicular helper cell response in primary Sjögren disease

Caveolin-1/PPARα axis suppresses T follicular helper cell response in primary Sjögren disease

Summary: T follicular helper (Tfh) cells play a central role in humoral autoimmunity, including primary Sjögren disease (SjD). However, targeting Tfh cells in clinical management is challenging. Previous studies suggest that inducible T cell co-stimulator (ICOS) directs Tfh cell motility in engaging...

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Bibliographic Details
Main Authors: Sulan Yu, Meiling Wu, Weizhen Zeng, Weiwei Fu, Yacun Chen, Jing Xie, Philip Hei Li, Yun Feng, Jiangang Shen, Xiang Lin
Format: Article
Language:English
Published: Elsevier 2025-08-01
Series:Cell Reports
Subjects:
CP: Immunology
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124725009271
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