Decoding bacterial methylomes in four public health-relevant microbial species: nanopore sequencing enables reproducible analysis of DNA modifications

Decoding bacterial methylomes in four public health-relevant microbial species: nanopore sequencing enables reproducible analysis of DNA modifications

Abstract Investigating bacterial methylation profiles provides essential complementary information to the native DNA sequence, significantly extending our understanding of how DNA modifications influence virulence, antibiotic resistance, and the ability of bacteria to evade the immune system. Recent...

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Bibliographic Details
Main Authors: Valentina Galeone, Johanna Dabernig-Heinz, Mara Lohde, Christian Brandt, Christian Kohler, Gabriel E. Wagner, Martin Hölzer
Format: Article
Language:English
Published: BMC 2025-04-01
Series:BMC Genomics
Subjects:
Nanopore
Methylation
Modkit
MicrobeMod
Methylome
R10
Online Access:https://doi.org/10.1186/s12864-025-11592-z
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