Viral Co-Infections and Antiviral Immunity in Honey Bees

Over the past few decades, honey bees have been facing an increasing number of stressors. Beyond individual stress factors, the synergies between them have been identified as a key factor in the observed increase in colony mortality. However, these interactions are numerous and complex and call for...

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Main Authors: Alice Mélusine Durand, Anne Bonjour-Dalmon, Eric Dubois
Format: Article
Language:English
Published: MDPI AG 2023-05-01
Series:Viruses
Subjects:
Online Access:https://www.mdpi.com/1999-4915/15/5/1217
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author Alice Mélusine Durand
Anne Bonjour-Dalmon
Eric Dubois
author_facet Alice Mélusine Durand
Anne Bonjour-Dalmon
Eric Dubois
author_sort Alice Mélusine Durand
collection DOAJ
description Over the past few decades, honey bees have been facing an increasing number of stressors. Beyond individual stress factors, the synergies between them have been identified as a key factor in the observed increase in colony mortality. However, these interactions are numerous and complex and call for further research. Here, in line with our need for a systemic understanding of the threats that they pose to bee health, we review the interactions between honey bee viruses. As viruses are obligate parasites, the interactions between them not only depend on the viruses themselves but also on the immune responses of honey bees. Thus, we first summarise our current knowledge of the antiviral immunity of honey bees. We then review the interactions between specific pathogenic viruses and their interactions with their host. Finally, we draw hypotheses from the current literature and suggest directions for future research.
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series Viruses
spelling doaj-art-c2bb30fa4ff946f09bfc9c0a25bfdf512025-08-20T03:27:52ZengMDPI AGViruses1999-49152023-05-01155121710.3390/v15051217Viral Co-Infections and Antiviral Immunity in Honey BeesAlice Mélusine Durand0Anne Bonjour-Dalmon1Eric Dubois2National Research Institute for Agriculture Food and Environement, INRAE, UR 406 Abeilles et Environnement, Site Agroparc, 84914 Avignon, FranceNational Research Institute for Agriculture Food and Environement, INRAE, UR 406 Abeilles et Environnement, Site Agroparc, 84914 Avignon, FranceFrench Agency for Food, Environmental and Occupational Health Safety, ANSES, 06902 Sophia Antipolis, FranceOver the past few decades, honey bees have been facing an increasing number of stressors. Beyond individual stress factors, the synergies between them have been identified as a key factor in the observed increase in colony mortality. However, these interactions are numerous and complex and call for further research. Here, in line with our need for a systemic understanding of the threats that they pose to bee health, we review the interactions between honey bee viruses. As viruses are obligate parasites, the interactions between them not only depend on the viruses themselves but also on the immune responses of honey bees. Thus, we first summarise our current knowledge of the antiviral immunity of honey bees. We then review the interactions between specific pathogenic viruses and their interactions with their host. Finally, we draw hypotheses from the current literature and suggest directions for future research.https://www.mdpi.com/1999-4915/15/5/1217virusinteractionsynergismimmune systemco-infectionhoney bee
spellingShingle Alice Mélusine Durand
Anne Bonjour-Dalmon
Eric Dubois
Viral Co-Infections and Antiviral Immunity in Honey Bees
Viruses
virus
interaction
synergism
immune system
co-infection
honey bee
title Viral Co-Infections and Antiviral Immunity in Honey Bees
title_full Viral Co-Infections and Antiviral Immunity in Honey Bees
title_fullStr Viral Co-Infections and Antiviral Immunity in Honey Bees
title_full_unstemmed Viral Co-Infections and Antiviral Immunity in Honey Bees
title_short Viral Co-Infections and Antiviral Immunity in Honey Bees
title_sort viral co infections and antiviral immunity in honey bees
topic virus
interaction
synergism
immune system
co-infection
honey bee
url https://www.mdpi.com/1999-4915/15/5/1217
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AT ericdubois viralcoinfectionsandantiviralimmunityinhoneybees