Cutaneous reactions to COVID‐19 vaccine at the dermatology primary care

Abstract Introduction Coronavirus disease 2019 (COVID‐19) vaccines can cause adverse reactions, mainly from vaccine‐induced immune responses. Some of these may also involve the skin and worry unaware patients. A better understanding of such adverse reactions may reduce concerns and help promote the...

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Main Authors: Martina Burlando, Astrid Herzum, Claudia Micalizzi, Emanuele Cozzani, Aurora Parodi
Format: Article
Language:English
Published: Wiley 2022-02-01
Series:Immunity, Inflammation and Disease
Subjects:
Online Access:https://doi.org/10.1002/iid3.568
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author Martina Burlando
Astrid Herzum
Claudia Micalizzi
Emanuele Cozzani
Aurora Parodi
author_facet Martina Burlando
Astrid Herzum
Claudia Micalizzi
Emanuele Cozzani
Aurora Parodi
author_sort Martina Burlando
collection DOAJ
description Abstract Introduction Coronavirus disease 2019 (COVID‐19) vaccines can cause adverse reactions, mainly from vaccine‐induced immune responses. Some of these may also involve the skin and worry unaware patients. A better understanding of such adverse reactions may reduce concerns and help promote the vaccination of large population groups. Methods All the reports of patients admitted to our Dermatology Primary Care, from March 2021 to June 2021, were retrospectively examined to collect descriptive data on skin reactions arising after COVID‐19 vaccination. Results Out of 200 vaccinated patients admitted to the Dermatology Primary Care, 21 (10.5%) referred cutaneous reactions with onset after vaccination. Only one patient required hospitalization for generalized bullous erythema multiforme, which occurred 48 h after the second vaccine dose. The other patients' cutaneous reactions to vaccination were of mild/moderate degree. Three patients presented exacerbation of their cutaneous diseases. Conclusions Cutaneous reactions observed in our sample were mostly mild or moderate. Awareness must be raised to recognize and treat eventual severe reactions. Future studies are needed to assess the incidence of cutaneous reactions following COVID‐19 vaccination.
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spelling doaj-art-c2ba4a6fbbc9441c9416f0f4be0ddba52025-08-20T03:08:46ZengWileyImmunity, Inflammation and Disease2050-45272022-02-0110226527110.1002/iid3.568Cutaneous reactions to COVID‐19 vaccine at the dermatology primary careMartina Burlando0Astrid Herzum1Claudia Micalizzi2Emanuele Cozzani3Aurora Parodi4Department of Health Sciences (DISSAL), Section of Dermatology, San Martino Polyclinic Hospital IRCCS, Largo R University of Genova Genova ItalyDepartment of Health Sciences (DISSAL), Section of Dermatology, San Martino Polyclinic Hospital IRCCS, Largo R University of Genova Genova ItalyDepartment of Health Sciences (DISSAL), Section of Dermatology, San Martino Polyclinic Hospital IRCCS, Largo R University of Genova Genova ItalyDepartment of Health Sciences (DISSAL), Section of Dermatology, San Martino Polyclinic Hospital IRCCS, Largo R University of Genova Genova ItalyDepartment of Health Sciences (DISSAL), Section of Dermatology, San Martino Polyclinic Hospital IRCCS, Largo R University of Genova Genova ItalyAbstract Introduction Coronavirus disease 2019 (COVID‐19) vaccines can cause adverse reactions, mainly from vaccine‐induced immune responses. Some of these may also involve the skin and worry unaware patients. A better understanding of such adverse reactions may reduce concerns and help promote the vaccination of large population groups. Methods All the reports of patients admitted to our Dermatology Primary Care, from March 2021 to June 2021, were retrospectively examined to collect descriptive data on skin reactions arising after COVID‐19 vaccination. Results Out of 200 vaccinated patients admitted to the Dermatology Primary Care, 21 (10.5%) referred cutaneous reactions with onset after vaccination. Only one patient required hospitalization for generalized bullous erythema multiforme, which occurred 48 h after the second vaccine dose. The other patients' cutaneous reactions to vaccination were of mild/moderate degree. Three patients presented exacerbation of their cutaneous diseases. Conclusions Cutaneous reactions observed in our sample were mostly mild or moderate. Awareness must be raised to recognize and treat eventual severe reactions. Future studies are needed to assess the incidence of cutaneous reactions following COVID‐19 vaccination.https://doi.org/10.1002/iid3.568coronavirus vaccineCOVID‐19 skinCOVID‐19 urticariaCOVID‐19 vaccination reactionCOVID‐19 vaccine rashvaccine allergy
spellingShingle Martina Burlando
Astrid Herzum
Claudia Micalizzi
Emanuele Cozzani
Aurora Parodi
Cutaneous reactions to COVID‐19 vaccine at the dermatology primary care
Immunity, Inflammation and Disease
coronavirus vaccine
COVID‐19 skin
COVID‐19 urticaria
COVID‐19 vaccination reaction
COVID‐19 vaccine rash
vaccine allergy
title Cutaneous reactions to COVID‐19 vaccine at the dermatology primary care
title_full Cutaneous reactions to COVID‐19 vaccine at the dermatology primary care
title_fullStr Cutaneous reactions to COVID‐19 vaccine at the dermatology primary care
title_full_unstemmed Cutaneous reactions to COVID‐19 vaccine at the dermatology primary care
title_short Cutaneous reactions to COVID‐19 vaccine at the dermatology primary care
title_sort cutaneous reactions to covid 19 vaccine at the dermatology primary care
topic coronavirus vaccine
COVID‐19 skin
COVID‐19 urticaria
COVID‐19 vaccination reaction
COVID‐19 vaccine rash
vaccine allergy
url https://doi.org/10.1002/iid3.568
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AT emanuelecozzani cutaneousreactionstocovid19vaccineatthedermatologyprimarycare
AT auroraparodi cutaneousreactionstocovid19vaccineatthedermatologyprimarycare