Etiological role and molecular-genetic features of <i>Streptococcus pneumoniae</i> in children’s infectious diseases
Objective: To study the etiological role, serotype distribution and prevalent Streptococcus pneumoniae genotypes (sequence types) in 459 children hospitalized with acute purulent otitis media, acute tonsillitis, community-acquired pneumonia, and purulent bacterial meningitis. Pneumococcal cultures i...
Saved in:
| Main Authors: | , , , , , , |
|---|---|
| Format: | Article |
| Language: | Russian |
| Published: |
LLC "Diagnostics and Vaccines"
2020-03-01
|
| Series: | Детские инфекции (Москва) |
| Subjects: | |
| Online Access: | https://detinf.elpub.ru/jour/article/view/475 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1850233687585587200 |
|---|---|
| author | I. N. Protasova G. P. Martynova N. A. Ilyenkova I. A. Kutischeva S. V. Domracheva O. P. Ovchinnikova E. S. Sokolovskaya |
| author_facet | I. N. Protasova G. P. Martynova N. A. Ilyenkova I. A. Kutischeva S. V. Domracheva O. P. Ovchinnikova E. S. Sokolovskaya |
| author_sort | I. N. Protasova |
| collection | DOAJ |
| description | Objective: To study the etiological role, serotype distribution and prevalent Streptococcus pneumoniae genotypes (sequence types) in 459 children hospitalized with acute purulent otitis media, acute tonsillitis, community-acquired pneumonia, and purulent bacterial meningitis. Pneumococcal cultures isolated from patients were tested for sensitivity to antimicrobials, and presence of resistance genes.Materials and Methods: The cultural and molecular methods (PCR, sequencing) were used. Statistical analysis was carried out using Microsoft Excel 2007 and Statistica 6.0. Results: S. pneumoniae was detected in 16,8%. The prevalent serotypes were 19F (39.7%) and 19A (13.2%) — representatives of multidrug-resistant clonal com-plex 320. Isolates of serogroup 6 (6AB, 8.82%) belonged to clonal complex 315, and characterized by resistance to macrolides, clindamycin and tetracycline.From 70.6% to 88.2% of S. pneumoniae serotypes isolated from patients corresponded to «vaccine»-types. |
| format | Article |
| id | doaj-art-c2b8f8d73b724ed58d68b7c34d0da6ed |
| institution | OA Journals |
| issn | 2072-8107 |
| language | Russian |
| publishDate | 2020-03-01 |
| publisher | LLC "Diagnostics and Vaccines" |
| record_format | Article |
| series | Детские инфекции (Москва) |
| spelling | doaj-art-c2b8f8d73b724ed58d68b7c34d0da6ed2025-08-20T02:02:51ZrusLLC "Diagnostics and Vaccines"Детские инфекции (Москва)2072-81072020-03-0119171210.22627/2072-8107-2020-19-1-7-12432Etiological role and molecular-genetic features of <i>Streptococcus pneumoniae</i> in children’s infectious diseasesI. N. Protasova0G. P. Martynova1N. A. Ilyenkova2I. A. Kutischeva3S. V. Domracheva4O. P. Ovchinnikova5E. S. Sokolovskaya6Professor V.F. Voino-Yasenetsky Krasnoyarsk State Medical UniversityProfessor V.F. Voino-Yasenetsky Krasnoyarsk State Medical UniversityProfessor V.F. Voino-Yasenetsky Krasnoyarsk State Medical UniversityProfessor V.F. Voino-Yasenetsky Krasnoyarsk State Medical UniversityKrasnoyarsk Interregional Children’s Hospital № 4Krasnoyarsk Interregional Children’s Clinical Hospital №1Professor V.F. Voino-Yasenetsky Krasnoyarsk State Medical UniversityObjective: To study the etiological role, serotype distribution and prevalent Streptococcus pneumoniae genotypes (sequence types) in 459 children hospitalized with acute purulent otitis media, acute tonsillitis, community-acquired pneumonia, and purulent bacterial meningitis. Pneumococcal cultures isolated from patients were tested for sensitivity to antimicrobials, and presence of resistance genes.Materials and Methods: The cultural and molecular methods (PCR, sequencing) were used. Statistical analysis was carried out using Microsoft Excel 2007 and Statistica 6.0. Results: S. pneumoniae was detected in 16,8%. The prevalent serotypes were 19F (39.7%) and 19A (13.2%) — representatives of multidrug-resistant clonal com-plex 320. Isolates of serogroup 6 (6AB, 8.82%) belonged to clonal complex 315, and characterized by resistance to macrolides, clindamycin and tetracycline.From 70.6% to 88.2% of S. pneumoniae serotypes isolated from patients corresponded to «vaccine»-types.https://detinf.elpub.ru/jour/article/view/475<i>streptococcus pneumoniae</i>pneumococcusetiological roleserotypes in childrensequence-typesresistance |
| spellingShingle | I. N. Protasova G. P. Martynova N. A. Ilyenkova I. A. Kutischeva S. V. Domracheva O. P. Ovchinnikova E. S. Sokolovskaya Etiological role and molecular-genetic features of <i>Streptococcus pneumoniae</i> in children’s infectious diseases Детские инфекции (Москва) <i>streptococcus pneumoniae</i> pneumococcus etiological role serotypes in children sequence-types resistance |
| title | Etiological role and molecular-genetic features of <i>Streptococcus pneumoniae</i> in children’s infectious diseases |
| title_full | Etiological role and molecular-genetic features of <i>Streptococcus pneumoniae</i> in children’s infectious diseases |
| title_fullStr | Etiological role and molecular-genetic features of <i>Streptococcus pneumoniae</i> in children’s infectious diseases |
| title_full_unstemmed | Etiological role and molecular-genetic features of <i>Streptococcus pneumoniae</i> in children’s infectious diseases |
| title_short | Etiological role and molecular-genetic features of <i>Streptococcus pneumoniae</i> in children’s infectious diseases |
| title_sort | etiological role and molecular genetic features of i streptococcus pneumoniae i in children s infectious diseases |
| topic | <i>streptococcus pneumoniae</i> pneumococcus etiological role serotypes in children sequence-types resistance |
| url | https://detinf.elpub.ru/jour/article/view/475 |
| work_keys_str_mv | AT inprotasova etiologicalroleandmoleculargeneticfeaturesofistreptococcuspneumoniaeiinchildrensinfectiousdiseases AT gpmartynova etiologicalroleandmoleculargeneticfeaturesofistreptococcuspneumoniaeiinchildrensinfectiousdiseases AT nailyenkova etiologicalroleandmoleculargeneticfeaturesofistreptococcuspneumoniaeiinchildrensinfectiousdiseases AT iakutischeva etiologicalroleandmoleculargeneticfeaturesofistreptococcuspneumoniaeiinchildrensinfectiousdiseases AT svdomracheva etiologicalroleandmoleculargeneticfeaturesofistreptococcuspneumoniaeiinchildrensinfectiousdiseases AT opovchinnikova etiologicalroleandmoleculargeneticfeaturesofistreptococcuspneumoniaeiinchildrensinfectiousdiseases AT essokolovskaya etiologicalroleandmoleculargeneticfeaturesofistreptococcuspneumoniaeiinchildrensinfectiousdiseases |