Continuous in situ synthesis of a complete set of tRNAs sustains steady-state translation in a recombinant cell-free system
Abstract Construction of a self-regenerating biochemical system is critical for building a synthetic cell. An essential step in building a self-regenerative system is producing a complete set of tRNAs for translation, which remains a significant challenge. Here, we reconstitute a complete set of 21...
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| Main Authors: | Fanjun Li, Amogh Kumar Baranwal, Sebastian J. Maerkl |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-07-01
|
| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-025-61671-8 |
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