A comprehensive review on the potential therapeutic benefits of prospective probiotic Christensenella minuta
Bacterial family Christensenellaceae performed high heritability and associated with human health status. Numerous studies observed that the abundance of Christensenellaceae could be significantly reduced in patients with intestinal diseases or metabolic disorders, inferred that it may be treated as...
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| Format: | Article |
| Language: | English |
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Tsinghua University Press
2025-06-01
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| Series: | Food Science and Human Wellness |
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| Online Access: | https://www.sciopen.com/article/10.26599/FSHW.2024.9250129 |
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| author | Yueyao Fan Yuhang Xiao Shiqing Zhang Weibin Bai Jiali Chen |
| author_facet | Yueyao Fan Yuhang Xiao Shiqing Zhang Weibin Bai Jiali Chen |
| author_sort | Yueyao Fan |
| collection | DOAJ |
| description | Bacterial family Christensenellaceae performed high heritability and associated with human health status. Numerous studies observed that the abundance of Christensenellaceae could be significantly reduced in patients with intestinal diseases or metabolic disorders, inferred that it may be treated as an effective biomarker. Christensenella minuta was the first member of Christensenellaceae family isolated from human fecal samples. Accumulating evidences suggested that C. minuta may demonstrate a positive bio-therapeutic effects toward unhealthy status. Hence, this review aimed to systematically summarize the characterization of Christensenellaceae under specific health or diseases, and discover its promising application. Besides, the latest studies on the pharmacological research of C. minuta also summarized. Current important literatures grasped the potential health benefits of C. minuta in managing metabolic disorders, gut ecosystem, and inflammation. Whereas, several critical knowledge gaps about the safe and clinical application remain should be addressed in future verification. C. minuta is worthy to be elevated as the next prospective probiotic star in nutraceutical or medical field and should not be overlooked. |
| format | Article |
| id | doaj-art-c2a975a6b2dc4c169de4379205a5750f |
| institution | DOAJ |
| issn | 2097-0765 2213-4530 |
| language | English |
| publishDate | 2025-06-01 |
| publisher | Tsinghua University Press |
| record_format | Article |
| series | Food Science and Human Wellness |
| spelling | doaj-art-c2a975a6b2dc4c169de4379205a5750f2025-08-20T02:58:11ZengTsinghua University PressFood Science and Human Wellness2097-07652213-45302025-06-01146925012910.26599/FSHW.2024.9250129A comprehensive review on the potential therapeutic benefits of prospective probiotic Christensenella minutaYueyao Fan0Yuhang Xiao1Shiqing Zhang2Weibin Bai3Jiali Chen4Department of Food Science and Engineering, College of Life Science and Technology, Jinan University, Guangzhou 510632, ChinaDepartment of Food Science and Engineering, College of Life Science and Technology, Jinan University, Guangzhou 510632, ChinaState Key Laboratory of Bioactive Molecules and Druggability Assessment, JNU-HKUST Joint Laboratory for Neuroscience and Innovative Drug Research, College of Pharmacy, Jinan University, Guangzhou 510632, ChinaDepartment of Food Science and Engineering, College of Life Science and Technology, Jinan University, Guangzhou 510632, ChinaDepartment of Food Science and Engineering, College of Life Science and Technology, Jinan University, Guangzhou 510632, ChinaBacterial family Christensenellaceae performed high heritability and associated with human health status. Numerous studies observed that the abundance of Christensenellaceae could be significantly reduced in patients with intestinal diseases or metabolic disorders, inferred that it may be treated as an effective biomarker. Christensenella minuta was the first member of Christensenellaceae family isolated from human fecal samples. Accumulating evidences suggested that C. minuta may demonstrate a positive bio-therapeutic effects toward unhealthy status. Hence, this review aimed to systematically summarize the characterization of Christensenellaceae under specific health or diseases, and discover its promising application. Besides, the latest studies on the pharmacological research of C. minuta also summarized. Current important literatures grasped the potential health benefits of C. minuta in managing metabolic disorders, gut ecosystem, and inflammation. Whereas, several critical knowledge gaps about the safe and clinical application remain should be addressed in future verification. C. minuta is worthy to be elevated as the next prospective probiotic star in nutraceutical or medical field and should not be overlooked.https://www.sciopen.com/article/10.26599/FSHW.2024.9250129gut microbiotachristensenellaceaechristensenella minutabiomarkerbiotherapy |
| spellingShingle | Yueyao Fan Yuhang Xiao Shiqing Zhang Weibin Bai Jiali Chen A comprehensive review on the potential therapeutic benefits of prospective probiotic Christensenella minuta Food Science and Human Wellness gut microbiota christensenellaceae christensenella minuta biomarker biotherapy |
| title | A comprehensive review on the potential therapeutic benefits of prospective probiotic Christensenella minuta |
| title_full | A comprehensive review on the potential therapeutic benefits of prospective probiotic Christensenella minuta |
| title_fullStr | A comprehensive review on the potential therapeutic benefits of prospective probiotic Christensenella minuta |
| title_full_unstemmed | A comprehensive review on the potential therapeutic benefits of prospective probiotic Christensenella minuta |
| title_short | A comprehensive review on the potential therapeutic benefits of prospective probiotic Christensenella minuta |
| title_sort | comprehensive review on the potential therapeutic benefits of prospective probiotic christensenella minuta |
| topic | gut microbiota christensenellaceae christensenella minuta biomarker biotherapy |
| url | https://www.sciopen.com/article/10.26599/FSHW.2024.9250129 |
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