Apoptotic cells induce NF-κB and inflammasome negative signaling.
As they undergo phagocytosis, most early apoptotic cells negatively regulate proinflammatory signaling and were suggested as a major mechanism in the resolution of inflammation. The dextran sulfate sodium model is generally viewed as an epithelial damage model suited to investigate innate immune res...
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| Main Authors: | Amir Grau, Adi Tabib, Inna Grau, Inna Reiner, Dror Mevorach |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2015-01-01
|
| Series: | PLoS ONE |
| Online Access: | https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0122440&type=printable |
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