Role of galectin-9 in the development of gestational diabetes mellitus

Role of galectin-9 in the development of gestational diabetes mellitus

Abstract Galectin-9 (Gal-9) is highly expressed in trophoblasts in placenta. Interaction between Gal-9 and T-cell immunoglobulin and mucin-domain containing-3 (Tim-3) is important for the differentiation of tissue resident natural killer (trNK) cells in placenta and maintenance of normal pregnancy....

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Main Authors: Haya Hamed Hassan Albuayjan, Mayu Watanabe, Ryosuke Sugawara, Eri Katsuyama, Koki Mise, Yukiko Oi, Ayaka Kanno, BoXuan Yang, Toshihisa Tahara, Ichiro Nojima, Atsuko Nakatsuka, Jun Eguchi, Jota Maki, Eriko Eto, Kei Hayata, Hisashi Masuyama, Jun Wada
Format: Article
Language:English
Published: Nature Portfolio 2025-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-025-03879-8
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