Intravitreal Aflibercept as a Rescue Therapy for Retinal Neovascularization and Macular Edema due to Eales Disease
We report the rescue effect of intravitreal aflibercept injections on retinal neovascularization and macular edema due to Eales disease. Case 1 was a 36-year-old female. Intravitreal aflibercept was administered as rescue therapy after persistent retinal neovascularization following retinal photocoa...
Saved in:
| Main Authors: | , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2021-01-01
|
| Series: | Case Reports in Ophthalmological Medicine |
| Online Access: | http://dx.doi.org/10.1155/2021/8887362 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832564913272258560 |
|---|---|
| author | Ning-Yi Hsia Chun-Ju Lin Chun-Ting Lai Henry Bair Cheng-Hsien Chang Jane-Ming Lin Yi-Yu Tsai |
| author_facet | Ning-Yi Hsia Chun-Ju Lin Chun-Ting Lai Henry Bair Cheng-Hsien Chang Jane-Ming Lin Yi-Yu Tsai |
| author_sort | Ning-Yi Hsia |
| collection | DOAJ |
| description | We report the rescue effect of intravitreal aflibercept injections on retinal neovascularization and macular edema due to Eales disease. Case 1 was a 36-year-old female. Intravitreal aflibercept was administered as rescue therapy after persistent retinal neovascularization following retinal photocoagulation, periocular triamcinolone, and intravitreal ranibizumab injection. Retinal neovascularization initially regressed, but recurred after 5 months along with macular edema. Two more intravitreal aflibercept injections were given, and retinal neovascularization with macular edema regressed. Her vision improved to 20/25 and remained stable after 43 months. Case 2 was a 27-year-old female. Intravitreal aflibercept was administered after persistent retinal neovascularization and macular edema following periocular triamcinolone injection. The macular edema initially subsided but recurred after 3 months. Intravitreal aflibercept injections were then administered once every three months to maintain her vision 20/20. The patient has been followed up for 28 months. Intravitreal aflibercept was effective as a rescue therapy in the treatment of Eales disease to regress retinal neovascularization, though repeated injections were necessary in cases of recurrence. |
| format | Article |
| id | doaj-art-c27bf20b4446479a938e6df6b34ccc43 |
| institution | Kabale University |
| issn | 2090-6722 2090-6730 |
| language | English |
| publishDate | 2021-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Ophthalmological Medicine |
| spelling | doaj-art-c27bf20b4446479a938e6df6b34ccc432025-02-03T01:09:56ZengWileyCase Reports in Ophthalmological Medicine2090-67222090-67302021-01-01202110.1155/2021/88873628887362Intravitreal Aflibercept as a Rescue Therapy for Retinal Neovascularization and Macular Edema due to Eales DiseaseNing-Yi Hsia0Chun-Ju Lin1Chun-Ting Lai2Henry Bair3Cheng-Hsien Chang4Jane-Ming Lin5Yi-Yu Tsai6Department of Ophthalmology, China Medical University Hospital, China Medical University, Taichung, TaiwanDepartment of Ophthalmology, China Medical University Hospital, China Medical University, Taichung, TaiwanDepartment of Ophthalmology, China Medical University Hospital, China Medical University, Taichung, TaiwanDepartment of Ophthalmology, China Medical University Hospital, China Medical University, Taichung, TaiwanDepartment of Ophthalmology, China Medical University Hospital, China Medical University, Taichung, TaiwanDepartment of Ophthalmology, China Medical University Hospital, China Medical University, Taichung, TaiwanDepartment of Ophthalmology, China Medical University Hospital, China Medical University, Taichung, TaiwanWe report the rescue effect of intravitreal aflibercept injections on retinal neovascularization and macular edema due to Eales disease. Case 1 was a 36-year-old female. Intravitreal aflibercept was administered as rescue therapy after persistent retinal neovascularization following retinal photocoagulation, periocular triamcinolone, and intravitreal ranibizumab injection. Retinal neovascularization initially regressed, but recurred after 5 months along with macular edema. Two more intravitreal aflibercept injections were given, and retinal neovascularization with macular edema regressed. Her vision improved to 20/25 and remained stable after 43 months. Case 2 was a 27-year-old female. Intravitreal aflibercept was administered after persistent retinal neovascularization and macular edema following periocular triamcinolone injection. The macular edema initially subsided but recurred after 3 months. Intravitreal aflibercept injections were then administered once every three months to maintain her vision 20/20. The patient has been followed up for 28 months. Intravitreal aflibercept was effective as a rescue therapy in the treatment of Eales disease to regress retinal neovascularization, though repeated injections were necessary in cases of recurrence.http://dx.doi.org/10.1155/2021/8887362 |
| spellingShingle | Ning-Yi Hsia Chun-Ju Lin Chun-Ting Lai Henry Bair Cheng-Hsien Chang Jane-Ming Lin Yi-Yu Tsai Intravitreal Aflibercept as a Rescue Therapy for Retinal Neovascularization and Macular Edema due to Eales Disease Case Reports in Ophthalmological Medicine |
| title | Intravitreal Aflibercept as a Rescue Therapy for Retinal Neovascularization and Macular Edema due to Eales Disease |
| title_full | Intravitreal Aflibercept as a Rescue Therapy for Retinal Neovascularization and Macular Edema due to Eales Disease |
| title_fullStr | Intravitreal Aflibercept as a Rescue Therapy for Retinal Neovascularization and Macular Edema due to Eales Disease |
| title_full_unstemmed | Intravitreal Aflibercept as a Rescue Therapy for Retinal Neovascularization and Macular Edema due to Eales Disease |
| title_short | Intravitreal Aflibercept as a Rescue Therapy for Retinal Neovascularization and Macular Edema due to Eales Disease |
| title_sort | intravitreal aflibercept as a rescue therapy for retinal neovascularization and macular edema due to eales disease |
| url | http://dx.doi.org/10.1155/2021/8887362 |
| work_keys_str_mv | AT ningyihsia intravitrealafliberceptasarescuetherapyforretinalneovascularizationandmacularedemaduetoealesdisease AT chunjulin intravitrealafliberceptasarescuetherapyforretinalneovascularizationandmacularedemaduetoealesdisease AT chuntinglai intravitrealafliberceptasarescuetherapyforretinalneovascularizationandmacularedemaduetoealesdisease AT henrybair intravitrealafliberceptasarescuetherapyforretinalneovascularizationandmacularedemaduetoealesdisease AT chenghsienchang intravitrealafliberceptasarescuetherapyforretinalneovascularizationandmacularedemaduetoealesdisease AT janeminglin intravitrealafliberceptasarescuetherapyforretinalneovascularizationandmacularedemaduetoealesdisease AT yiyutsai intravitrealafliberceptasarescuetherapyforretinalneovascularizationandmacularedemaduetoealesdisease |