Impact of TP53 codon 72 and MDM2 SNP 309 polymorphisms in pancreatic ductal adenocarcinoma.

Impact of TP53 codon 72 and MDM2 SNP 309 polymorphisms in pancreatic ductal adenocarcinoma.

Single-nucleotide polymorphisms (SNPs) of TP53 (codon 72, rs1042522) and MDM2 promoter (SNP 309, rs2279744) have been associated with risk for various human cancers. However, studies analyzing these polymorphisms in pancreatic ductal adenocarcinoma (PDAC) are lacking. We investigated TP53 codon 72 a...

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Main Authors: Yasuki Hori, Katsuyuki Miyabe, Michihiro Yoshida, Takahiro Nakazawa, Kazuki Hayashi, Itaru Naitoh, Shuya Shimizu, Hiromu Kondo, Yuji Nishi, Shuichiro Umemura, Akihisa Kato, Hirotaka Ohara, Hiroshi Inagaki, Takashi Joh
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0118829&type=printable
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