A Review of Complicated Cataract in Retinitis Pigmentosa: Pathogenesis and Cataract Surgery
Retinitis pigmentosa (RP) is a set of inherited retinal degenerative diseases that affect photoreceptor and retinal pigment epithelial cells (RPEs), possibly associated with some ocular complications, including cataract. The complicated cataract formation is most likely the result of RP-related infl...
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| Format: | Article |
| Language: | English |
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Wiley
2020-01-01
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| Series: | Journal of Ophthalmology |
| Online Access: | http://dx.doi.org/10.1155/2020/6699103 |
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| author | Yingying Hong Hongzhe Li Yang Sun Yinghong Ji |
| author_facet | Yingying Hong Hongzhe Li Yang Sun Yinghong Ji |
| author_sort | Yingying Hong |
| collection | DOAJ |
| description | Retinitis pigmentosa (RP) is a set of inherited retinal degenerative diseases that affect photoreceptor and retinal pigment epithelial cells (RPEs), possibly associated with some ocular complications, including cataract. The complicated cataract formation is most likely the result of RP-related inflammation response, and the most common morphology category is posterior subcapsular cataract (PSC). Despite the absence of curative pharmacologic treatment, phacoemulsification with intraocular lens implantation to deal with opacification in the lens is preferred due to the considerable visual outcomes. However, the incidence of intraocular and postoperative complications is higher in RP patients than those without, including intraoperative phototoxic retinal damage, posterior capsular opacification (PCO), capsular contraction syndrome (CCS), pseudophakic cystoid macular edema (PCME), increased postoperative intraocular pressure (IOP), and intraocular lens (IOL) dislocation. Hence, it needs much attention to surgery progress and close follow-up. In this review, we discuss the current understanding of RP patients with complicated cataracts from morphology to potential pathogenesis to cataract surgical procedure and provide a concise description and the recommended management of related surgery complications to broaden the knowledge and lower the latent risks to yield better clinical outcomes. |
| format | Article |
| id | doaj-art-c2702284aa5b4424bfad79b54fe63282 |
| institution | Kabale University |
| issn | 2090-004X 2090-0058 |
| language | English |
| publishDate | 2020-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Ophthalmology |
| spelling | doaj-art-c2702284aa5b4424bfad79b54fe632822025-02-03T06:00:48ZengWileyJournal of Ophthalmology2090-004X2090-00582020-01-01202010.1155/2020/66991036699103A Review of Complicated Cataract in Retinitis Pigmentosa: Pathogenesis and Cataract SurgeryYingying Hong0Hongzhe Li1Yang Sun2Yinghong Ji3Eye Institute and Department of Ophthalmology, Eye & ENT Hospital, Fudan University, Shanghai 200031, ChinaEye Institute and Department of Ophthalmology, Eye & ENT Hospital, Fudan University, Shanghai 200031, ChinaEye Institute and Department of Ophthalmology, Eye & ENT Hospital, Fudan University, Shanghai 200031, ChinaEye Institute and Department of Ophthalmology, Eye & ENT Hospital, Fudan University, Shanghai 200031, ChinaRetinitis pigmentosa (RP) is a set of inherited retinal degenerative diseases that affect photoreceptor and retinal pigment epithelial cells (RPEs), possibly associated with some ocular complications, including cataract. The complicated cataract formation is most likely the result of RP-related inflammation response, and the most common morphology category is posterior subcapsular cataract (PSC). Despite the absence of curative pharmacologic treatment, phacoemulsification with intraocular lens implantation to deal with opacification in the lens is preferred due to the considerable visual outcomes. However, the incidence of intraocular and postoperative complications is higher in RP patients than those without, including intraoperative phototoxic retinal damage, posterior capsular opacification (PCO), capsular contraction syndrome (CCS), pseudophakic cystoid macular edema (PCME), increased postoperative intraocular pressure (IOP), and intraocular lens (IOL) dislocation. Hence, it needs much attention to surgery progress and close follow-up. In this review, we discuss the current understanding of RP patients with complicated cataracts from morphology to potential pathogenesis to cataract surgical procedure and provide a concise description and the recommended management of related surgery complications to broaden the knowledge and lower the latent risks to yield better clinical outcomes.http://dx.doi.org/10.1155/2020/6699103 |
| spellingShingle | Yingying Hong Hongzhe Li Yang Sun Yinghong Ji A Review of Complicated Cataract in Retinitis Pigmentosa: Pathogenesis and Cataract Surgery Journal of Ophthalmology |
| title | A Review of Complicated Cataract in Retinitis Pigmentosa: Pathogenesis and Cataract Surgery |
| title_full | A Review of Complicated Cataract in Retinitis Pigmentosa: Pathogenesis and Cataract Surgery |
| title_fullStr | A Review of Complicated Cataract in Retinitis Pigmentosa: Pathogenesis and Cataract Surgery |
| title_full_unstemmed | A Review of Complicated Cataract in Retinitis Pigmentosa: Pathogenesis and Cataract Surgery |
| title_short | A Review of Complicated Cataract in Retinitis Pigmentosa: Pathogenesis and Cataract Surgery |
| title_sort | review of complicated cataract in retinitis pigmentosa pathogenesis and cataract surgery |
| url | http://dx.doi.org/10.1155/2020/6699103 |
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