Impact of nebulizers on nanoparticles-based gene delivery efficiency: in vitro and in vivo comparison of jet and mesh nebulizers using branched-polyethyleneimine

Impact of nebulizers on nanoparticles-based gene delivery efficiency: in vitro and in vivo comparison of jet and mesh nebulizers using branched-polyethyleneimine

Nanoparticles-based gene delivery has emerged as a promising approach for the treatment of genetic diseases based on efficient delivery systems for therapeutic nucleic acids (NAs) into the target cells. For pulmonary diseases such as cystic fibrosis (CF), chronic obstructive pulmonary diseases (COPD...

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Bibliographic Details
Main Authors: Rosy Ghanem, Xavier Buin, Tanguy Haute, Justine Philippe, Ghalia Kaouane, Lara Leclerc, Maël Guivarch, Tony Le Gall, Jérémie Pourchez, Tristan Montier
Format: Article
Language:English
Published: Taylor & Francis Group 2025-12-01
Series:Drug Delivery
Subjects:
Gene delivery
aerosol
nebulization
branched-polyethyleneimine
lung
jet nebulizer
Online Access:https://www.tandfonline.com/doi/10.1080/10717544.2025.2463428
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https://www.tandfonline.com/doi/10.1080/10717544.2025.2463428

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