ALCAM-mediated cDC1 CD8 T cells interactions are suppressed in advanced lung tumors

ALCAM-mediated cDC1 CD8 T cells interactions are suppressed in advanced lung tumors

Conventional type 1 dendritic cells (cDC1) are critical regulators of anti-tumoral T-cell responses. The structure and abundance of intercellular contacts between cDC1 and CD8 T cells in cancer tissues is important to determine the outcome of the T-cell response. However, the molecular determinants...

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Bibliographic Details
Main Authors: Luciano G. Morosi, Giulia M. Piperno, Lucía López, Roberto Amadio, Sonal Joshi, Alessandra Rustighi, Giannino Del Sal, Federica Benvenuti
Format: Article
Language:English
Published: Taylor & Francis Group 2024-12-01
Series:OncoImmunology
Subjects:
ALCAM
cDC1
immunological synapse
lung cancer
NSCLC
Online Access:https://www.tandfonline.com/doi/10.1080/2162402X.2024.2367843
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https://www.tandfonline.com/doi/10.1080/2162402X.2024.2367843

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