Data-independent LC-MS/MS analysis of ME/CFS plasma reveals a dysregulated coagulation system, endothelial dysfunction, downregulation of complement machinery

Data-independent LC-MS/MS analysis of ME/CFS plasma reveals a dysregulated coagulation system, endothelial dysfunction, downregulation of complement machinery

Abstract Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a debilitating chronic condition that is characterized by unresolved fatigue, post-exertion symptom exacerbation (PESE), cognitive dysfunction, orthostatic intolerance, and other symptoms. ME/CFS lacks established clinical bioma...

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Bibliographic Details
Main Authors: Massimo Nunes, Mare Vlok, Amy Proal, Douglas B. Kell, Etheresia Pretorius
Format: Article
Language:English
Published: BMC 2024-07-01
Series:Cardiovascular Diabetology
Subjects:
Myalgic encephalomyelitis/Chronic fatigue syndrome (ME/CFS)
Proteomics
Thrombotic pathology
Endothelial pathology
Online Access:https://doi.org/10.1186/s12933-024-02315-x
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https://doi.org/10.1186/s12933-024-02315-x

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