Identification and impact of microbiota-derived metabolites in ascites of ovarian and gastrointestinal cancer

Identification and impact of microbiota-derived metabolites in ascites of ovarian and gastrointestinal cancer

Abstract Background Malignant ascites is a common complication of advanced ovarian cancer (OC) and gastrointestinal cancer (GI), significantly impacting metastasis, quality of life, and survival. Increased intestinal permeability can lead to blood or lymphatic infiltration and microbial translocatio...

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Main Authors: Sisi Deng, Wooyong Kim, Kefan Cheng, Qianlu Yang, Yogesh Singh, Gyuntae Bae, Nicolas Bézière, Lukas Mager, Stefan Kommoss, Jannik Sprengel, Christoph Trautwein
Format: Article
Language:English
Published: BMC 2025-05-01
Series:Cancer & Metabolism
Subjects:
Microbiota
Malignant Ascites
TimsTOF
Flow cytometry
MiMeDB
Online Access:https://doi.org/10.1186/s40170-025-00391-5
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