Comprehensive genomic profiling reveals a unique genomic landscape in solid tumors in an Indian cancer cohort of 1000 patients: a single institutional experience

Comprehensive genomic profiling reveals a unique genomic landscape in solid tumors in an Indian cancer cohort of 1000 patients: a single institutional experience

Abstract The use of Comprehensive Genomic Profiling (CGP) in clinical practice to detect broad-spectrum therapeutic, prognostic, and predictive biomarkers, including tumor mutational burden (TMB), microsatellite instability (MSI), somatic BRCA (sBRCA) and other homologous recombination repair genes...

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Main Authors: Mithua Ghosh, Sheela Mysore Lingaraju, Krishna C.R, Gautam Balaram, Ramya Kodandapani, Vijay E, Vijay K, Suhas N, Devika H, Shekar Patil, Satheesh Chiradoni Thungappa, Somorat Bhattacharjee, Sridhar P.S, Roshni Dasgupta, Mohammed Naseer, Srinivas B.J, Vishal Rao, Veena Ramaswamy, Radheshyam Naik, Govind Babu, Aarthi Ravichandran, Urvashi Bahadur, Krithika Murugan, Mahesh B, Lohith Reddy, Ajaikumar Basavalinga S
Format: Article
Language:English
Published: Nature Portfolio 2025-04-01
Series:Scientific Reports
Subjects:
Comprehensive genomic profiling
Next-generation sequencing
Precision oncology
Targeted therapy
Immunotherapy
Multidisciplinary molecular tumor board
Online Access:https://doi.org/10.1038/s41598-025-94762-z
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