Vitiligo Review: etiopathogenesis, diagnosis and treatment
Introduction and purpose:This review is intended for healthcare professionals, including dermatologists, primary care physicians, and researchers, who seek a comprehensive understanding of vitiligo. It is also relevant for patients and their families to better understand the condition. The review i...
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| Language: | English |
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Nicolaus Copernicus University in Toruń
2025-01-01
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| Series: | Quality in Sport |
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| Online Access: | https://apcz.umk.pl/QS/article/view/57367 |
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| author | Aleksandra Witek Jakub Parys Agnieszka Mikosińska Martyna Kaźmierczak Maciej Mossakowski Patrycja Kałuziak Marta Jajczak Mateusz Litwin Stanisław Jesionek RAfał Bieś |
| author_facet | Aleksandra Witek Jakub Parys Agnieszka Mikosińska Martyna Kaźmierczak Maciej Mossakowski Patrycja Kałuziak Marta Jajczak Mateusz Litwin Stanisław Jesionek RAfał Bieś |
| author_sort | Aleksandra Witek |
| collection | DOAJ |
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Introduction and purpose:This review is intended for healthcare professionals, including dermatologists, primary care physicians, and researchers, who seek a comprehensive understanding of vitiligo. It is also relevant for patients and their families to better understand the condition. The review is indicated for those dealing with cases of vitiligo that are difficult to diagnose or manage, those with widespread or refractory vitiligo, and individuals interested in the latest advancements in treatment. The purpose of this review is to provide a detailed analysis of vitiligo’s etiopathogenesis, the current diagnostic methods, and the most effective treatment options. By exploring the genetic, autoimmune, and environmental factors involved in vitiligo, the review aims to enhance the understanding of the disease's origin and progression. Additionally, it seeks to offer evidence-based insights into the most up-to-date diagnostic tools and therapeutic approaches, ultimately improving patient care and guiding future research directions.
State of knowledge:
Vitiligo is an autoimmune disorder characterized by the loss of melanocytes, leading to depigmented skin patches. Its exact cause remains unclear, but genetic and environmental factors, such as stress and skin trauma, are thought to contribute. Diagnosis is primarily clinical, with dermoscopy and biopsy used in uncertain cases. While treatments like topical corticosteroids, phototherapy, and JAK inhibitors are effective for some, no cure exists, and responses vary widely. Surgical options like melanocyte transplantation can help with localized cases. Ongoing research aims to better understand the disease mechanisms and improve treatment outcomes.
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| format | Article |
| id | doaj-art-c24504aacf7a4707879bca89b9569e4e |
| institution | Kabale University |
| issn | 2450-3118 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Nicolaus Copernicus University in Toruń |
| record_format | Article |
| series | Quality in Sport |
| spelling | doaj-art-c24504aacf7a4707879bca89b9569e4e2025-01-14T08:22:48ZengNicolaus Copernicus University in ToruńQuality in Sport2450-31182025-01-013710.12775/QS.2025.37.57367Vitiligo Review: etiopathogenesis, diagnosis and treatmentAleksandra Witek0https://orcid.org/0009-0002-1214-2199Jakub Parys1https://orcid.org/0009-0009-1955-7865Agnieszka Mikosińska2https://orcid.org/0009-0003-0891-9089Martyna Kaźmierczak3https://orcid.org/0009-0007-7798-0069Maciej Mossakowski4https://orcid.org/0009-0008-0423-2083Patrycja Kałuziak5https://orcid.org/0009-0008-0976-1523Marta Jajczak6https://orcid.org/0009-0009-6000-7769Mateusz Litwin7https://orcid.org/0009-0006-5131-1863Stanisław Jesionek8https://orcid.org/0009-0004-6026-702XRAfał Bieś9https://orcid.org/0009-0005-0583-6661Central Clinical Hospital of Medical University of Lodz, ul. Pomorska 251, 92-213 Łódź, PolandCentral Clinical Hospital of Medical University of Lodz, ul. Pomorska 251, 92-213 Łódź, PolandCentral Clinical Hospital of Medical University of Lodz, ul. Pomorska 251, 92-213 Łódź, PolandCentral Clinical Hospital of Medical University of Lodz, ul. Pomorska 251, 92-213 Łódź, PolandCentral Clinical Hospital of Medical University of Lodz, ul. Pomorska 251, 92-213 Łódź, PolandCharles Jonscher Medical Center, ul. Milionowa 14, 93-113 Łódź, PolandUniversity Clinical Hospital No.2 of Medical University of Lodz, ul. Żeromskiego 113, 90-549 Łódź, PolandUniversity Clinical Hospital No.2 of Medical University of Lodz, ul. Żeromskiego 113, 90-549 Łódź, PolandPabianice Medical Center Sp. o.o., ul. Jana Pawła II 68, 95-200 Pabianice, PolandMedical University of Silesia, Faculty of Medical Sciences in Katowice, ul. Medyków 18, 40-752 Katowice, Poland Introduction and purpose:This review is intended for healthcare professionals, including dermatologists, primary care physicians, and researchers, who seek a comprehensive understanding of vitiligo. It is also relevant for patients and their families to better understand the condition. The review is indicated for those dealing with cases of vitiligo that are difficult to diagnose or manage, those with widespread or refractory vitiligo, and individuals interested in the latest advancements in treatment. The purpose of this review is to provide a detailed analysis of vitiligo’s etiopathogenesis, the current diagnostic methods, and the most effective treatment options. By exploring the genetic, autoimmune, and environmental factors involved in vitiligo, the review aims to enhance the understanding of the disease's origin and progression. Additionally, it seeks to offer evidence-based insights into the most up-to-date diagnostic tools and therapeutic approaches, ultimately improving patient care and guiding future research directions. State of knowledge: Vitiligo is an autoimmune disorder characterized by the loss of melanocytes, leading to depigmented skin patches. Its exact cause remains unclear, but genetic and environmental factors, such as stress and skin trauma, are thought to contribute. Diagnosis is primarily clinical, with dermoscopy and biopsy used in uncertain cases. While treatments like topical corticosteroids, phototherapy, and JAK inhibitors are effective for some, no cure exists, and responses vary widely. Surgical options like melanocyte transplantation can help with localized cases. Ongoing research aims to better understand the disease mechanisms and improve treatment outcomes. https://apcz.umk.pl/QS/article/view/57367vitiligophototherapyautoimmune diseasesmelanocytescorticosteroids |
| spellingShingle | Aleksandra Witek Jakub Parys Agnieszka Mikosińska Martyna Kaźmierczak Maciej Mossakowski Patrycja Kałuziak Marta Jajczak Mateusz Litwin Stanisław Jesionek RAfał Bieś Vitiligo Review: etiopathogenesis, diagnosis and treatment Quality in Sport vitiligo phototherapy autoimmune diseases melanocytes corticosteroids |
| title | Vitiligo Review: etiopathogenesis, diagnosis and treatment |
| title_full | Vitiligo Review: etiopathogenesis, diagnosis and treatment |
| title_fullStr | Vitiligo Review: etiopathogenesis, diagnosis and treatment |
| title_full_unstemmed | Vitiligo Review: etiopathogenesis, diagnosis and treatment |
| title_short | Vitiligo Review: etiopathogenesis, diagnosis and treatment |
| title_sort | vitiligo review etiopathogenesis diagnosis and treatment |
| topic | vitiligo phototherapy autoimmune diseases melanocytes corticosteroids |
| url | https://apcz.umk.pl/QS/article/view/57367 |
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