Mechanistic insights into the anti-aging and anti-cancer potential of rosemary via P53, SRC, and AKT1 through a network pharmacology perspective

Mechanistic insights into the anti-aging and anti-cancer potential of rosemary via P53, SRC, and AKT1 through a network pharmacology perspective

This study investigates the anti-aging and anticancer properties of rosemary extract, focusing on its bioactive compounds and their interactions with key proteins through network pharmacology and molecular docking. Bioactive compounds were identified using LC-HRMS and GC-MS, and in vitro assays test...

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Bibliographic Details
Main Authors: Trina Ekawati Tallei, Herlina Ineke Surjane Wungouw, Nurdjannah Jane Niode, Fatimawali Fatimawali, Maghfirah Savitri, Sofia Safitri Hessel, Dionisius Rafael Makawaehe, Fahrul Nurkolis
Format: Article
Language:English
Published: Taylor & Francis Group 2025-12-01
Series:CyTA - Journal of Food
Subjects:
Rosemary
signaling pathways
bioactive compounds
therapeutic targets
protein-protein interactions
anti-aging associated proteins
Online Access:https://www.tandfonline.com/doi/10.1080/19476337.2025.2504528
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