AAV-mediated expression of proneural factors stimulates neurogenesis from adult Müller glia in vivo
Abstract The lack of regeneration in the human central nervous system (CNS) has major health implications. To address this, we previously used transgenic mouse models to show that neurogenesis can be stimulated in the adult mammalian retina by driving regeneration programs that other species activat...
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| Main Authors: | Marina Pavlou, Marlene Probst, Lew Kaplan, Elizaveta Filippova, Aric R Prieve, Fred Rieke, Thomas A Reh |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Springer Nature
2025-03-01
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| Series: | EMBO Molecular Medicine |
| Subjects: | |
| Online Access: | https://doi.org/10.1038/s44321-025-00209-3 |
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