Pilocytic astrocytoma: A rare case report
Pilocytic astrocytoma (PA) is a rare, low-grade glioma predominantly affecting children and young adults, with a favorable prognosis and a high survival rate. Despite its’ slow growth, PA often presents with significant symptoms at diagnosis due to its tendency to reach a large size, especially in p...
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| Format: | Article |
| Language: | English |
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Elsevier
2025-04-01
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| Series: | Radiology Case Reports |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S1930043325000251 |
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| author | Harry Galuh Nugraha, PhD Elsa Yoasta, MD Mirna Sobana, MD Hermin Aminah Usman, MD |
| author_facet | Harry Galuh Nugraha, PhD Elsa Yoasta, MD Mirna Sobana, MD Hermin Aminah Usman, MD |
| author_sort | Harry Galuh Nugraha, PhD |
| collection | DOAJ |
| description | Pilocytic astrocytoma (PA) is a rare, low-grade glioma predominantly affecting children and young adults, with a favorable prognosis and a high survival rate. Despite its’ slow growth, PA often presents with significant symptoms at diagnosis due to its tendency to reach a large size, especially in pediatric patients, where compensatory mechanisms can delay detection. This case report describes a 7-year-old girl with progressive vision loss, headache, and balance disturbance. The imaging result revealed a right cerebellar mass that was in accordance with pilocytic astrocytoma and obstructive hydrocephalus. Histopathologic analysis confirmed the diagnosis with the typical features of PA such as Rosenthal fibers and eosinophilic granular bodies. This case report highlights the critical role of radiologic and histopathologic evaluations for PA diagnosis and management; also the unique presentation and challenges in managing PA, emphasizing the importance of timely intervention to optimize neurological outcomes. |
| format | Article |
| id | doaj-art-c238b243ef65463eaf6df53fd56e6867 |
| institution | Kabale University |
| issn | 1930-0433 |
| language | English |
| publishDate | 2025-04-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Radiology Case Reports |
| spelling | doaj-art-c238b243ef65463eaf6df53fd56e68672025-02-02T05:27:01ZengElsevierRadiology Case Reports1930-04332025-04-0120421752179Pilocytic astrocytoma: A rare case reportHarry Galuh Nugraha, PhD0Elsa Yoasta, MD1Mirna Sobana, MD2Hermin Aminah Usman, MD3Department of Radiology, Faculty of Medicine Padjadjaran University, Dr. Hasan Sadikin Hospital Bandung, Pasteur Num. 38, Pasteur, Sukajadi, Bandung, West Java 40161, IndonesiaDepartment of Radiology, Faculty of Medicine Padjadjaran University, Dr. Hasan Sadikin Hospital Bandung, Pasteur Num. 38, Pasteur, Sukajadi, Bandung, West Java 40161, Indonesia; Corresponding author.Department of Neurosurgery, Faculty of Medicine Padjadjaran University, Dr. Hasan Sadikin Hospital Bandung, Pasteur Num. 38, Pasteur, Sukajadi, Bandung, West Java 40161, IndonesiaDepartment of Pathology Anatomy, Faculty of Medicine Padjadjaran University, Dr. Hasan Sadikin Hospital Bandung, Pasteur Num. 38, Pasteur, Sukajadi, Bandung, West Java 40161, IndonesiaPilocytic astrocytoma (PA) is a rare, low-grade glioma predominantly affecting children and young adults, with a favorable prognosis and a high survival rate. Despite its’ slow growth, PA often presents with significant symptoms at diagnosis due to its tendency to reach a large size, especially in pediatric patients, where compensatory mechanisms can delay detection. This case report describes a 7-year-old girl with progressive vision loss, headache, and balance disturbance. The imaging result revealed a right cerebellar mass that was in accordance with pilocytic astrocytoma and obstructive hydrocephalus. Histopathologic analysis confirmed the diagnosis with the typical features of PA such as Rosenthal fibers and eosinophilic granular bodies. This case report highlights the critical role of radiologic and histopathologic evaluations for PA diagnosis and management; also the unique presentation and challenges in managing PA, emphasizing the importance of timely intervention to optimize neurological outcomes.http://www.sciencedirect.com/science/article/pii/S1930043325000251Pilocytic astrocytomaPediatric neuroradiologyHead CT scan |
| spellingShingle | Harry Galuh Nugraha, PhD Elsa Yoasta, MD Mirna Sobana, MD Hermin Aminah Usman, MD Pilocytic astrocytoma: A rare case report Radiology Case Reports Pilocytic astrocytoma Pediatric neuroradiology Head CT scan |
| title | Pilocytic astrocytoma: A rare case report |
| title_full | Pilocytic astrocytoma: A rare case report |
| title_fullStr | Pilocytic astrocytoma: A rare case report |
| title_full_unstemmed | Pilocytic astrocytoma: A rare case report |
| title_short | Pilocytic astrocytoma: A rare case report |
| title_sort | pilocytic astrocytoma a rare case report |
| topic | Pilocytic astrocytoma Pediatric neuroradiology Head CT scan |
| url | http://www.sciencedirect.com/science/article/pii/S1930043325000251 |
| work_keys_str_mv | AT harrygaluhnugrahaphd pilocyticastrocytomaararecasereport AT elsayoastamd pilocyticastrocytomaararecasereport AT mirnasobanamd pilocyticastrocytomaararecasereport AT herminaminahusmanmd pilocyticastrocytomaararecasereport |