Treatment Resistant Severe Digital Ischemia Associated with Antiphospholipid Syndrome in a Male Patient with Systemic Sclerosis

We report the case of a male patient with limited cutaneous systemic sclerosis (SSc) that was complicated with severe digital ischemia, resistant to medical treatment. Due to the lack of treatment response, further laboratory and imaging studies were conducted. Findings were compatible with antiphos...

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Main Authors: Orhan Küçükşahin, Aşkın Ateş, Alexis K. Okoh, Emre Kulahcioglu, Murat Turgay, Gülay Kınıklı
Format: Article
Language:English
Published: Wiley 2014-01-01
Series:Case Reports in Rheumatology
Online Access:http://dx.doi.org/10.1155/2014/291382
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author Orhan Küçükşahin
Aşkın Ateş
Alexis K. Okoh
Emre Kulahcioglu
Murat Turgay
Gülay Kınıklı
author_facet Orhan Küçükşahin
Aşkın Ateş
Alexis K. Okoh
Emre Kulahcioglu
Murat Turgay
Gülay Kınıklı
author_sort Orhan Küçükşahin
collection DOAJ
description We report the case of a male patient with limited cutaneous systemic sclerosis (SSc) that was complicated with severe digital ischemia, resistant to medical treatment. Due to the lack of treatment response, further laboratory and imaging studies were conducted. Findings were compatible with antiphospholipid syndrome and oral warfarin was added to the treatment regimen. After successful anticoagulation no further recurrences of digital ischemia were seen. An underlying etiology in SSc patients with treatment resistant digital ischemic necrosis should be suspected for accompanying antiphospholipid syndrome (APS).
format Article
id doaj-art-c2328d62c1344d73b0ec905c8cbc841c
institution OA Journals
issn 2090-6889
2090-6897
language English
publishDate 2014-01-01
publisher Wiley
record_format Article
series Case Reports in Rheumatology
spelling doaj-art-c2328d62c1344d73b0ec905c8cbc841c2025-08-20T02:19:03ZengWileyCase Reports in Rheumatology2090-68892090-68972014-01-01201410.1155/2014/291382291382Treatment Resistant Severe Digital Ischemia Associated with Antiphospholipid Syndrome in a Male Patient with Systemic SclerosisOrhan Küçükşahin0Aşkın Ateş1Alexis K. Okoh2Emre Kulahcioglu3Murat Turgay4Gülay Kınıklı5Department of Rheumatology, Ankara University Medical Faculty, Sihhiye, 06410 Ankara, TurkeyDepartment of Rheumatology, Ankara University Medical Faculty, Sihhiye, 06410 Ankara, TurkeyDepartment of Internal Medicine, Ankara University Medical Faculty, Sihhiye, 06410 Ankara, TurkeyDepartment of Internal Medicine, Ankara University Medical Faculty, Sihhiye, 06410 Ankara, TurkeyDepartment of Internal Medicine, Ankara University Medical Faculty, Sihhiye, 06410 Ankara, TurkeyDepartment of Rheumatology, Ankara University Medical Faculty, Sihhiye, 06410 Ankara, TurkeyWe report the case of a male patient with limited cutaneous systemic sclerosis (SSc) that was complicated with severe digital ischemia, resistant to medical treatment. Due to the lack of treatment response, further laboratory and imaging studies were conducted. Findings were compatible with antiphospholipid syndrome and oral warfarin was added to the treatment regimen. After successful anticoagulation no further recurrences of digital ischemia were seen. An underlying etiology in SSc patients with treatment resistant digital ischemic necrosis should be suspected for accompanying antiphospholipid syndrome (APS).http://dx.doi.org/10.1155/2014/291382
spellingShingle Orhan Küçükşahin
Aşkın Ateş
Alexis K. Okoh
Emre Kulahcioglu
Murat Turgay
Gülay Kınıklı
Treatment Resistant Severe Digital Ischemia Associated with Antiphospholipid Syndrome in a Male Patient with Systemic Sclerosis
Case Reports in Rheumatology
title Treatment Resistant Severe Digital Ischemia Associated with Antiphospholipid Syndrome in a Male Patient with Systemic Sclerosis
title_full Treatment Resistant Severe Digital Ischemia Associated with Antiphospholipid Syndrome in a Male Patient with Systemic Sclerosis
title_fullStr Treatment Resistant Severe Digital Ischemia Associated with Antiphospholipid Syndrome in a Male Patient with Systemic Sclerosis
title_full_unstemmed Treatment Resistant Severe Digital Ischemia Associated with Antiphospholipid Syndrome in a Male Patient with Systemic Sclerosis
title_short Treatment Resistant Severe Digital Ischemia Associated with Antiphospholipid Syndrome in a Male Patient with Systemic Sclerosis
title_sort treatment resistant severe digital ischemia associated with antiphospholipid syndrome in a male patient with systemic sclerosis
url http://dx.doi.org/10.1155/2014/291382
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