Life’s Crucial 9 Score as a Novel Role for Chronic Obstructive Pulmonary Disease Screening
Wenqiang Li,1,* Youli Wen,1,* Yuting Fan,2 Zefu Hu,3 Zhiping Deng,1 Qian Huang3 1Department of Respiratory and Critical Care Medicine, Zigong First People’s Hospital, Zigong, Sichuan Province, 643000, People’s Republic of China; 2Department of Clinical Medicine, North Sichuan...
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Dove Medical Press
2025-07-01
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| Series: | International Journal of COPD |
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| Online Access: | https://www.dovepress.com/lifes-crucial-9-score-as-a-novel-role-for-chronic-obstructive-pulmonar-peer-reviewed-fulltext-article-COPD |
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| author | Li W Wen Y Fan Y Hu Z Deng Z Huang Q |
| author_facet | Li W Wen Y Fan Y Hu Z Deng Z Huang Q |
| author_sort | Li W |
| collection | DOAJ |
| description | Wenqiang Li,1,* Youli Wen,1,* Yuting Fan,2 Zefu Hu,3 Zhiping Deng,1 Qian Huang3 1Department of Respiratory and Critical Care Medicine, Zigong First People’s Hospital, Zigong, Sichuan Province, 643000, People’s Republic of China; 2Department of Clinical Medicine, North Sichuan Medical College, Nanchong, Sichuan Province, 637000, People’s Republic of China; 3Department of Respiratory and Critical Care Medicine, Dazhou Dachuan District People’s Hospital (Dazhou Third People’s Hospital), Dazhou, Sichuan Province, 635000, People’s Republic of China*These authors contributed equally to this workCorrespondence: Qian Huang, Department of Respiratory and Critical Care Medicine, Dazhou Dachuan District People’s Hospital (Dazhou Third People’s Hospital), Dazhou, 635000, Sichuan Province, People’s Republic of China, Tel +8615196767955, Email hq15196767955@163.com Zhiping Deng, Department of Respiratory and Critical Care Medicine, Zigong First People’s Hospital, Zigong, 643000, Sichuan Province, People’s Republic of China, Tel +8613608158051, Email zgsdzp1016@163.comPurpose: This study aims to investigate the association between the Life’s Crucial 9 (LC9) score and chronic obstructive pulmonary disease (COPD) in middle-aged and older adults.Patients and Methods: We screened the NHANES database for data from 2007– 2018. Logistic regression analysis and subgroup analysis were used to explore the association between LC9 score and COPD in middle-aged and older adults. Additionally, restricted cubic spline (RCS) was plotted to visually depict the dose-response relationship between the two.Results: A total of 12,030 participants were included, of whom 815 had COPD. After multivariate adjustment, the LC9 score was found to be inversely associated with COPD diagnosis. The RCS visually demonstrated a linear decreasing relationship between the two. Furthermore, subgroup analysis revealed no significant interaction across different subgroups, except for education level.Conclusion: The LC9 score is linearly and inversely associated with COPD diagnosis. Higher LC9 scores are associated with a lower COPD diagnosis in individuals aged 40 and above.Keywords: COPD, middle-aged and older adults, life’s crucial 9, diagnosis, cardiovascular health |
| format | Article |
| id | doaj-art-c209076058554ffb8d52b10c5d0743f7 |
| institution | Kabale University |
| issn | 1178-2005 |
| language | English |
| publishDate | 2025-07-01 |
| publisher | Dove Medical Press |
| record_format | Article |
| series | International Journal of COPD |
| spelling | doaj-art-c209076058554ffb8d52b10c5d0743f72025-08-20T03:28:58ZengDove Medical PressInternational Journal of COPD1178-20052025-07-01Volume 20Issue 121612171104434Life’s Crucial 9 Score as a Novel Role for Chronic Obstructive Pulmonary Disease ScreeningLi WWen YFan Y0Hu ZDeng Z1Huang Q2Clinical MedicineDepartment of Pulmonary and Critical Care MedicineDepartment of Respiratory and Critical Care MedicineWenqiang Li,1,* Youli Wen,1,* Yuting Fan,2 Zefu Hu,3 Zhiping Deng,1 Qian Huang3 1Department of Respiratory and Critical Care Medicine, Zigong First People’s Hospital, Zigong, Sichuan Province, 643000, People’s Republic of China; 2Department of Clinical Medicine, North Sichuan Medical College, Nanchong, Sichuan Province, 637000, People’s Republic of China; 3Department of Respiratory and Critical Care Medicine, Dazhou Dachuan District People’s Hospital (Dazhou Third People’s Hospital), Dazhou, Sichuan Province, 635000, People’s Republic of China*These authors contributed equally to this workCorrespondence: Qian Huang, Department of Respiratory and Critical Care Medicine, Dazhou Dachuan District People’s Hospital (Dazhou Third People’s Hospital), Dazhou, 635000, Sichuan Province, People’s Republic of China, Tel +8615196767955, Email hq15196767955@163.com Zhiping Deng, Department of Respiratory and Critical Care Medicine, Zigong First People’s Hospital, Zigong, 643000, Sichuan Province, People’s Republic of China, Tel +8613608158051, Email zgsdzp1016@163.comPurpose: This study aims to investigate the association between the Life’s Crucial 9 (LC9) score and chronic obstructive pulmonary disease (COPD) in middle-aged and older adults.Patients and Methods: We screened the NHANES database for data from 2007– 2018. Logistic regression analysis and subgroup analysis were used to explore the association between LC9 score and COPD in middle-aged and older adults. Additionally, restricted cubic spline (RCS) was plotted to visually depict the dose-response relationship between the two.Results: A total of 12,030 participants were included, of whom 815 had COPD. After multivariate adjustment, the LC9 score was found to be inversely associated with COPD diagnosis. The RCS visually demonstrated a linear decreasing relationship between the two. Furthermore, subgroup analysis revealed no significant interaction across different subgroups, except for education level.Conclusion: The LC9 score is linearly and inversely associated with COPD diagnosis. Higher LC9 scores are associated with a lower COPD diagnosis in individuals aged 40 and above.Keywords: COPD, middle-aged and older adults, life’s crucial 9, diagnosis, cardiovascular healthhttps://www.dovepress.com/lifes-crucial-9-score-as-a-novel-role-for-chronic-obstructive-pulmonar-peer-reviewed-fulltext-article-COPDCOPDmiddle-aged and older adultsLife's Crucial 9diagnosiscardiovascular health |
| spellingShingle | Li W Wen Y Fan Y Hu Z Deng Z Huang Q Life’s Crucial 9 Score as a Novel Role for Chronic Obstructive Pulmonary Disease Screening International Journal of COPD COPD middle-aged and older adults Life's Crucial 9 diagnosis cardiovascular health |
| title | Life’s Crucial 9 Score as a Novel Role for Chronic Obstructive Pulmonary Disease Screening |
| title_full | Life’s Crucial 9 Score as a Novel Role for Chronic Obstructive Pulmonary Disease Screening |
| title_fullStr | Life’s Crucial 9 Score as a Novel Role for Chronic Obstructive Pulmonary Disease Screening |
| title_full_unstemmed | Life’s Crucial 9 Score as a Novel Role for Chronic Obstructive Pulmonary Disease Screening |
| title_short | Life’s Crucial 9 Score as a Novel Role for Chronic Obstructive Pulmonary Disease Screening |
| title_sort | life amp rsquo s crucial 9 score as a novel role for chronic obstructive pulmonary disease screening |
| topic | COPD middle-aged and older adults Life's Crucial 9 diagnosis cardiovascular health |
| url | https://www.dovepress.com/lifes-crucial-9-score-as-a-novel-role-for-chronic-obstructive-pulmonar-peer-reviewed-fulltext-article-COPD |
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