Particle Formation by Supercritical Fluid Extraction and Expansion Process
Supercritical fluid extraction and expansion (SFEE) patented technology combines the advantages of both supercritical fluid extraction (SFE) and rapid expansion of supercritical solution (RESS) with on-line coupling, which makes the nanoparticle formation feasible directly from matrix such as Chines...
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| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2013-01-01
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| Series: | The Scientific World Journal |
| Online Access: | http://dx.doi.org/10.1155/2013/538584 |
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| _version_ | 1832556635272249344 |
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| author | Sujuan Pan Junbo Zhou Haiting Li Can Quan |
| author_facet | Sujuan Pan Junbo Zhou Haiting Li Can Quan |
| author_sort | Sujuan Pan |
| collection | DOAJ |
| description | Supercritical fluid extraction and expansion (SFEE) patented technology combines the advantages of both supercritical fluid extraction (SFE) and rapid expansion of supercritical solution (RESS) with on-line coupling, which makes the nanoparticle formation feasible directly from matrix such as Chinese herbal medicine. Supercritical fluid extraction is a green separation technology, which has been developed for decades and widely applied in traditional Chinese medicines or natural active components. In this paper, a SFEE patented instrument was firstly built up and controlled by LABVIEW work stations. Stearic acid was used to verify the SFEE process at optimized condition; via adjusting the preexpansion pressure and temperature one can get different sizes of particles. Furthermore, stearic acid was purified during the SFEE process with HPLC-ELSD detecting device; purity of stearic acid increased by 19%, and the device can purify stearic acid. |
| format | Article |
| id | doaj-art-c1fc0c33baee4c75ade6202cdfe65050 |
| institution | Kabale University |
| issn | 1537-744X |
| language | English |
| publishDate | 2013-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | The Scientific World Journal |
| spelling | doaj-art-c1fc0c33baee4c75ade6202cdfe650502025-02-03T05:44:49ZengWileyThe Scientific World Journal1537-744X2013-01-01201310.1155/2013/538584538584Particle Formation by Supercritical Fluid Extraction and Expansion ProcessSujuan Pan0Junbo Zhou1Haiting Li2Can Quan3Engineering Research Center for Polymer Processing Equipment, Ministry of Education, School of Mechanical and Electrical Engineering, Beijing University of Chemical Technology, Beijing 100029, ChinaEngineering Research Center for Polymer Processing Equipment, Ministry of Education, School of Mechanical and Electrical Engineering, Beijing University of Chemical Technology, Beijing 100029, ChinaEngineering Research Center for Polymer Processing Equipment, Ministry of Education, School of Mechanical and Electrical Engineering, Beijing University of Chemical Technology, Beijing 100029, ChinaDivision of Chemical Metrology and Analytical Science, National Institute of Metrology, Beijing 100013, ChinaSupercritical fluid extraction and expansion (SFEE) patented technology combines the advantages of both supercritical fluid extraction (SFE) and rapid expansion of supercritical solution (RESS) with on-line coupling, which makes the nanoparticle formation feasible directly from matrix such as Chinese herbal medicine. Supercritical fluid extraction is a green separation technology, which has been developed for decades and widely applied in traditional Chinese medicines or natural active components. In this paper, a SFEE patented instrument was firstly built up and controlled by LABVIEW work stations. Stearic acid was used to verify the SFEE process at optimized condition; via adjusting the preexpansion pressure and temperature one can get different sizes of particles. Furthermore, stearic acid was purified during the SFEE process with HPLC-ELSD detecting device; purity of stearic acid increased by 19%, and the device can purify stearic acid.http://dx.doi.org/10.1155/2013/538584 |
| spellingShingle | Sujuan Pan Junbo Zhou Haiting Li Can Quan Particle Formation by Supercritical Fluid Extraction and Expansion Process The Scientific World Journal |
| title | Particle Formation by Supercritical Fluid Extraction and Expansion Process |
| title_full | Particle Formation by Supercritical Fluid Extraction and Expansion Process |
| title_fullStr | Particle Formation by Supercritical Fluid Extraction and Expansion Process |
| title_full_unstemmed | Particle Formation by Supercritical Fluid Extraction and Expansion Process |
| title_short | Particle Formation by Supercritical Fluid Extraction and Expansion Process |
| title_sort | particle formation by supercritical fluid extraction and expansion process |
| url | http://dx.doi.org/10.1155/2013/538584 |
| work_keys_str_mv | AT sujuanpan particleformationbysupercriticalfluidextractionandexpansionprocess AT junbozhou particleformationbysupercriticalfluidextractionandexpansionprocess AT haitingli particleformationbysupercriticalfluidextractionandexpansionprocess AT canquan particleformationbysupercriticalfluidextractionandexpansionprocess |