Daxx Variation as a Potential Predictive Marker of the Therapeutic Response to Neoadjuvant Chemoradiotherapy in Locally Advanced Rectal Cancer

Daxx Variation as a Potential Predictive Marker of the Therapeutic Response to Neoadjuvant Chemoradiotherapy in Locally Advanced Rectal Cancer

ABSTRACT Objective The response to neoadjuvant chemoradiotherapy (NACRT) for locally advanced rectal cancer (LARC) varies from achieving a complete pathological response to encountering resistance to treatment. Therefore, biomarkers for predicting the NACRT responses should be identified. This prosp...

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Bibliographic Details
Main Authors: Xi Zhu, Xiaoming Kao, Leilei Liu, Xuan Wang, Yang Li, Qiurong Li
Format: Article
Language:English
Published: Wiley 2025-03-01
Series:Cancer Medicine
Subjects:
Daxx
locally advanced rectal cancer
neoadjuvant chemoradiotherapy
predictive biomarker
therapeutic response
Online Access:https://doi.org/10.1002/cam4.70815
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