Chemical Composition, Chemometric Analysis, and Sensory Profile of <i>Santolina chamaecyparissus L.</i> (<i>Asteraceae</i>) Essential Oil: Insights from a Case Study in Serbia and Literature-Based Review
The flowers of <i>Santolina chamaecyparissus</i> have a distinct aroma and taste, with a wide range of applications in medicine, food, and packaging. Its essential oil offers numerous health benefits, including antioxidant, hepatoprotective, anticancer, antidiabetic, spasmolytic, anti-in...
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2025-05-01
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| author | Biljana Lončar Mirjana Cvetković Milica Rat Jovana Stanković Jeremić Jelena Filipović Lato Pezo Milica Aćimović |
| author_facet | Biljana Lončar Mirjana Cvetković Milica Rat Jovana Stanković Jeremić Jelena Filipović Lato Pezo Milica Aćimović |
| author_sort | Biljana Lončar |
| collection | DOAJ |
| description | The flowers of <i>Santolina chamaecyparissus</i> have a distinct aroma and taste, with a wide range of applications in medicine, food, and packaging. Its essential oil offers numerous health benefits, including antioxidant, hepatoprotective, anticancer, antidiabetic, spasmolytic, anti-inflammatory, immunomodulatory, antimicrobial, and antiparasitic properties. Additionally, it is used as a flavoring agent in food and beverages and as a natural preservative in edible coatings for food packaging. This study investigates the chemical composition and sensory properties of the <i>S. chamaecyparissus</i> essential oil from Serbia, obtained via hydrodistillation, and includes a literature-based analysis of the existing profiles. Gas Chromatography–Mass Spectrometry (GC–MS) was employed for identifying the essential oil composition, while chemometric techniques like the genetic algorithm (GA), quantitative structure–retention relationship (QSRR) analysis, artificial neural network (ANN), and molecular descriptors were applied to ensure accurate and reliable results for authenticating the oil. Among the 47 identified compounds, oxygenated monoterpenes, especially artemisia ketone (36.11%), and oxygenated sesquiterpenes, notably vulgarone B (22.13%), were the primary constituents. Chemometric analysis proved effective in predicting the oil’s composition, and sensory evaluation revealed a herbal aroma with earthy, woody, and camphoraceous notes. A literature review highlighted the variability in oil composition due to geographical, environmental, and extraction factors, underscoring its chemical diversity, bioactivity, and potential applications. |
| format | Article |
| id | doaj-art-c1ed342a362e4ce5a52b9ec5df74d79f |
| institution | OA Journals |
| issn | 2297-8739 |
| language | English |
| publishDate | 2025-05-01 |
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| spelling | doaj-art-c1ed342a362e4ce5a52b9ec5df74d79f2025-08-20T01:56:45ZengMDPI AGSeparations2297-87392025-05-0112511510.3390/separations12050115Chemical Composition, Chemometric Analysis, and Sensory Profile of <i>Santolina chamaecyparissus L.</i> (<i>Asteraceae</i>) Essential Oil: Insights from a Case Study in Serbia and Literature-Based ReviewBiljana Lončar0Mirjana Cvetković1Milica Rat2Jovana Stanković Jeremić3Jelena Filipović4Lato Pezo5Milica Aćimović6Faculty of Technology Novi Sad, University of Novi Sad, Bulevar cara Lazara 1, 21000 Novi Sad, SerbiaInstitute of Chemistry, Technology and Metallurgy (IHTM)—National Institute of the Republic of Serbia, University of Belgrade, Njegoševa 12, 11000 Belgrade, SerbiaFaculty of Science, University of Novi Sad, Trg Dositeja Obradovića 3, 21000 Novi Sad, SerbiaInstitute of Chemistry, Technology and Metallurgy (IHTM)—National Institute of the Republic of Serbia, University of Belgrade, Njegoševa 12, 11000 Belgrade, SerbiaInstitute of Food Technology, University of Novi Sad, Bulevar cara Lazara 1, 21000 Novi Sad, SerbiaInstitute of General and Physical Chemistry, University of Belgrade, Studentski Trg 12-16, 11000 Belgrade, SerbiaInstitute of Field and Vegetable Crops Novi Sad (IFVCNS)—National Institute of the Republic of Serbia, Maksima Gorkog 30, 21000 Novi Sad, SerbiaThe flowers of <i>Santolina chamaecyparissus</i> have a distinct aroma and taste, with a wide range of applications in medicine, food, and packaging. Its essential oil offers numerous health benefits, including antioxidant, hepatoprotective, anticancer, antidiabetic, spasmolytic, anti-inflammatory, immunomodulatory, antimicrobial, and antiparasitic properties. Additionally, it is used as a flavoring agent in food and beverages and as a natural preservative in edible coatings for food packaging. This study investigates the chemical composition and sensory properties of the <i>S. chamaecyparissus</i> essential oil from Serbia, obtained via hydrodistillation, and includes a literature-based analysis of the existing profiles. Gas Chromatography–Mass Spectrometry (GC–MS) was employed for identifying the essential oil composition, while chemometric techniques like the genetic algorithm (GA), quantitative structure–retention relationship (QSRR) analysis, artificial neural network (ANN), and molecular descriptors were applied to ensure accurate and reliable results for authenticating the oil. Among the 47 identified compounds, oxygenated monoterpenes, especially artemisia ketone (36.11%), and oxygenated sesquiterpenes, notably vulgarone B (22.13%), were the primary constituents. Chemometric analysis proved effective in predicting the oil’s composition, and sensory evaluation revealed a herbal aroma with earthy, woody, and camphoraceous notes. A literature review highlighted the variability in oil composition due to geographical, environmental, and extraction factors, underscoring its chemical diversity, bioactivity, and potential applications.https://www.mdpi.com/2297-8739/12/5/115volatile compoundsartemisia ketonevulgarone Bchemotypescluster analysischemometrics |
| spellingShingle | Biljana Lončar Mirjana Cvetković Milica Rat Jovana Stanković Jeremić Jelena Filipović Lato Pezo Milica Aćimović Chemical Composition, Chemometric Analysis, and Sensory Profile of <i>Santolina chamaecyparissus L.</i> (<i>Asteraceae</i>) Essential Oil: Insights from a Case Study in Serbia and Literature-Based Review Separations volatile compounds artemisia ketone vulgarone B chemotypes cluster analysis chemometrics |
| title | Chemical Composition, Chemometric Analysis, and Sensory Profile of <i>Santolina chamaecyparissus L.</i> (<i>Asteraceae</i>) Essential Oil: Insights from a Case Study in Serbia and Literature-Based Review |
| title_full | Chemical Composition, Chemometric Analysis, and Sensory Profile of <i>Santolina chamaecyparissus L.</i> (<i>Asteraceae</i>) Essential Oil: Insights from a Case Study in Serbia and Literature-Based Review |
| title_fullStr | Chemical Composition, Chemometric Analysis, and Sensory Profile of <i>Santolina chamaecyparissus L.</i> (<i>Asteraceae</i>) Essential Oil: Insights from a Case Study in Serbia and Literature-Based Review |
| title_full_unstemmed | Chemical Composition, Chemometric Analysis, and Sensory Profile of <i>Santolina chamaecyparissus L.</i> (<i>Asteraceae</i>) Essential Oil: Insights from a Case Study in Serbia and Literature-Based Review |
| title_short | Chemical Composition, Chemometric Analysis, and Sensory Profile of <i>Santolina chamaecyparissus L.</i> (<i>Asteraceae</i>) Essential Oil: Insights from a Case Study in Serbia and Literature-Based Review |
| title_sort | chemical composition chemometric analysis and sensory profile of i santolina chamaecyparissus l i i asteraceae i essential oil insights from a case study in serbia and literature based review |
| topic | volatile compounds artemisia ketone vulgarone B chemotypes cluster analysis chemometrics |
| url | https://www.mdpi.com/2297-8739/12/5/115 |
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