Adherencia farmacológica y factores asociados en diabéticos tipo 2 en el Instituto Nacional del Diabético
Introduction: A key aspect in the management of type 2 diabetes is medication adherence.In 2023, The overall prevalence of medication adherence was 55%. Objective: To determine the proportion and associated factors of medication adherence in type 2 diabetes pat...
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Colegio Médico de Honduras
2025-06-01
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| Series: | Revista Médica Hondureña |
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| Online Access: | https://www.camjol.info/index.php/RMH/article/view/20546 |
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| author | Augusto Alfonso Rosales Meléndez Clares Shayra Pérez Mitchel Senaedy Borjas Barahona |
| author_facet | Augusto Alfonso Rosales Meléndez Clares Shayra Pérez Mitchel Senaedy Borjas Barahona |
| author_sort | Augusto Alfonso Rosales Meléndez |
| collection | DOAJ |
| description | Introduction: A key aspect in the management of type 2 diabetes is medication adherence.In 2023, The overall prevalence of medication adherence was 55%. Objective: To determine the proportion and associated factors of medication adherence in type 2 diabetes patients at the National Institute of Diabetes (INADI) from May to July 2024. Methods: Cross-sectional study with association analysis conducted in adults (≥18 years) with type 2 diabetes, using non-probabilistic quota sampling. A survey was applied, and adherence was assessed using the Morisky-Green scale. The statistical analysis included univariate, bivariate, and multivariate approaches, applying robust Poisson regression. Crude and adjusted prevalence ratios (PR) were estimated, with 95% confidence intervals (CI) and p values ≤0.05. Results: A percentage of medication adherence of 61% was found. The associated factors include high family income (PR: 1.40, 95%CI 1.07-1.83, p=0.01), more than 10 years with the disease (PR: 1.35, 95%CI 1.01-1.82, p=0.04), a positive attitude towards medication (PR: 2.45, 95%CI 1.11-5.39, p =0.02), and consistent family support (PR: 1.41, 95%CI 1.03-1.94, p=0.04). Adverse effects such as hypoglycemia (PR: 0.64, 95%CI 0.49-0.83, p=0.001) and gastrointestinal side effects (PR: 0.68, 95%CI 0.48-0.94, p=0.02) were negatively associated with adherence. Discussion: Medication adherence in type 2 diabetes is influenced by psychosocial, economic, and clinical factors. Addressing these aspects in therapeutic strategies could improve adherence and disease management |
| format | Article |
| id | doaj-art-c1ec2efe7cbe42b1a871f1f5f2879a12 |
| institution | Kabale University |
| issn | 0375-1112 1995-7068 |
| language | Spanish |
| publishDate | 2025-06-01 |
| publisher | Colegio Médico de Honduras |
| record_format | Article |
| series | Revista Médica Hondureña |
| spelling | doaj-art-c1ec2efe7cbe42b1a871f1f5f2879a122025-08-20T03:35:38ZspaColegio Médico de HondurasRevista Médica Hondureña0375-11121995-70682025-06-0193 1455310.5377/rmh.v93i1.20546Adherencia farmacológica y factores asociados en diabéticos tipo 2 en el Instituto Nacional del DiabéticoAugusto Alfonso Rosales Meléndez0https://orcid.org/0009-0006-7894-2534Clares Shayra Pérez1https://orcid.org/0000-0003-3877-6464Mitchel Senaedy Borjas Barahona2https://orcid.org/0009-0003-6012-4136Profesional independiente; Tegucigalpa, Honduras.Lackawanna County Health Department; Pensilvania, Estados Unidos.Instituto Nacional del Diabético, Dirección de investigación; Tegucigalpa, Honduras.Introduction: A key aspect in the management of type 2 diabetes is medication adherence.In 2023, The overall prevalence of medication adherence was 55%. Objective: To determine the proportion and associated factors of medication adherence in type 2 diabetes patients at the National Institute of Diabetes (INADI) from May to July 2024. Methods: Cross-sectional study with association analysis conducted in adults (≥18 years) with type 2 diabetes, using non-probabilistic quota sampling. A survey was applied, and adherence was assessed using the Morisky-Green scale. The statistical analysis included univariate, bivariate, and multivariate approaches, applying robust Poisson regression. Crude and adjusted prevalence ratios (PR) were estimated, with 95% confidence intervals (CI) and p values ≤0.05. Results: A percentage of medication adherence of 61% was found. The associated factors include high family income (PR: 1.40, 95%CI 1.07-1.83, p=0.01), more than 10 years with the disease (PR: 1.35, 95%CI 1.01-1.82, p=0.04), a positive attitude towards medication (PR: 2.45, 95%CI 1.11-5.39, p =0.02), and consistent family support (PR: 1.41, 95%CI 1.03-1.94, p=0.04). Adverse effects such as hypoglycemia (PR: 0.64, 95%CI 0.49-0.83, p=0.001) and gastrointestinal side effects (PR: 0.68, 95%CI 0.48-0.94, p=0.02) were negatively associated with adherence. Discussion: Medication adherence in type 2 diabetes is influenced by psychosocial, economic, and clinical factors. Addressing these aspects in therapeutic strategies could improve adherence and disease managementhttps://www.camjol.info/index.php/RMH/article/view/20546diabetes mellitustype 2family supportmedication adherencepatient compliancetreatment adherence and compliance |
| spellingShingle | Augusto Alfonso Rosales Meléndez Clares Shayra Pérez Mitchel Senaedy Borjas Barahona Adherencia farmacológica y factores asociados en diabéticos tipo 2 en el Instituto Nacional del Diabético Revista Médica Hondureña diabetes mellitus type 2 family support medication adherence patient compliance treatment adherence and compliance |
| title | Adherencia farmacológica y factores asociados en diabéticos tipo 2 en el Instituto Nacional del Diabético |
| title_full | Adherencia farmacológica y factores asociados en diabéticos tipo 2 en el Instituto Nacional del Diabético |
| title_fullStr | Adherencia farmacológica y factores asociados en diabéticos tipo 2 en el Instituto Nacional del Diabético |
| title_full_unstemmed | Adherencia farmacológica y factores asociados en diabéticos tipo 2 en el Instituto Nacional del Diabético |
| title_short | Adherencia farmacológica y factores asociados en diabéticos tipo 2 en el Instituto Nacional del Diabético |
| title_sort | adherencia farmacologica y factores asociados en diabeticos tipo 2 en el instituto nacional del diabetico |
| topic | diabetes mellitus type 2 family support medication adherence patient compliance treatment adherence and compliance |
| url | https://www.camjol.info/index.php/RMH/article/view/20546 |
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