Treatment of Severe Hypertriglyceridemia with Continuous Insulin Infusion
Severe hypertriglyceridemia (SH) represents a therapeutic emergency because of the possibility of developing cardiovascular events and hyperlipemic acute pancreatitis (PA). Most patients with SH suffer primary or genetic abnormality in lipid metabolism in combination with a precipitating factor such...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2011-01-01
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| Series: | Case Reports in Critical Care |
| Online Access: | http://dx.doi.org/10.1155/2011/293917 |
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| author | Yesica Rodríguez Santana Andrea Nimo Román Iker García Sáez José Manuel López Alvarez Eduardo Consuegra Llapur Rafael González Jorge |
| author_facet | Yesica Rodríguez Santana Andrea Nimo Román Iker García Sáez José Manuel López Alvarez Eduardo Consuegra Llapur Rafael González Jorge |
| author_sort | Yesica Rodríguez Santana |
| collection | DOAJ |
| description | Severe hypertriglyceridemia (SH) represents a therapeutic emergency because of the possibility of developing cardiovascular events and hyperlipemic acute pancreatitis (PA). Most patients with SH suffer primary or genetic abnormality in lipid metabolism in combination with a precipitating factor such as uncontrolled diabetes mellitus, alcoholism, and drug intake. The standard treatment of hypertriglyceridemia (HTG) with omega 3 fatty acids and fibrates, along with dietary changes, has no effect on an emergency situation. There are no clinical guidelines to SH, but therapy with insulin, heparin, a combination of both, plasmapheresis, or octreotide have been tested succesfully. We report the case of a 10-year-old girl with clinical acute pancreatitis and diabetic ketoacidosis debut, along with incidental finding of an SH, who had a good outcome after treatment with insulin intravenous infusion. |
| format | Article |
| id | doaj-art-c1e827f172954bf089f77d0355c32b56 |
| institution | Kabale University |
| issn | 2090-6420 2090-6439 |
| language | English |
| publishDate | 2011-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Critical Care |
| spelling | doaj-art-c1e827f172954bf089f77d0355c32b562025-02-03T05:53:49ZengWileyCase Reports in Critical Care2090-64202090-64392011-01-01201110.1155/2011/293917293917Treatment of Severe Hypertriglyceridemia with Continuous Insulin InfusionYesica Rodríguez Santana0Andrea Nimo Román1Iker García Sáez2José Manuel López Alvarez3Eduardo Consuegra Llapur4Rafael González Jorge5Pediatric Intensive Care Unit, Hospital Universitario Materno-Infantil, 35016 Las Palmas de Gran Canaria, SpainPediatric Intensive Care Unit, Hospital Universitario Materno-Infantil, 35016 Las Palmas de Gran Canaria, SpainPediatric Intensive Care Unit, Hospital Universitario Materno-Infantil, 35016 Las Palmas de Gran Canaria, SpainPediatric Intensive Care Unit, Hospital Universitario Materno-Infantil, 35016 Las Palmas de Gran Canaria, SpainPediatric Intensive Care Unit, Hospital Universitario Materno-Infantil, 35016 Las Palmas de Gran Canaria, SpainPediatric Intensive Care Unit, Hospital Universitario Materno-Infantil, 35016 Las Palmas de Gran Canaria, SpainSevere hypertriglyceridemia (SH) represents a therapeutic emergency because of the possibility of developing cardiovascular events and hyperlipemic acute pancreatitis (PA). Most patients with SH suffer primary or genetic abnormality in lipid metabolism in combination with a precipitating factor such as uncontrolled diabetes mellitus, alcoholism, and drug intake. The standard treatment of hypertriglyceridemia (HTG) with omega 3 fatty acids and fibrates, along with dietary changes, has no effect on an emergency situation. There are no clinical guidelines to SH, but therapy with insulin, heparin, a combination of both, plasmapheresis, or octreotide have been tested succesfully. We report the case of a 10-year-old girl with clinical acute pancreatitis and diabetic ketoacidosis debut, along with incidental finding of an SH, who had a good outcome after treatment with insulin intravenous infusion.http://dx.doi.org/10.1155/2011/293917 |
| spellingShingle | Yesica Rodríguez Santana Andrea Nimo Román Iker García Sáez José Manuel López Alvarez Eduardo Consuegra Llapur Rafael González Jorge Treatment of Severe Hypertriglyceridemia with Continuous Insulin Infusion Case Reports in Critical Care |
| title | Treatment of Severe Hypertriglyceridemia with Continuous Insulin Infusion |
| title_full | Treatment of Severe Hypertriglyceridemia with Continuous Insulin Infusion |
| title_fullStr | Treatment of Severe Hypertriglyceridemia with Continuous Insulin Infusion |
| title_full_unstemmed | Treatment of Severe Hypertriglyceridemia with Continuous Insulin Infusion |
| title_short | Treatment of Severe Hypertriglyceridemia with Continuous Insulin Infusion |
| title_sort | treatment of severe hypertriglyceridemia with continuous insulin infusion |
| url | http://dx.doi.org/10.1155/2011/293917 |
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