Tear Replacement Therapy in Medical Support of Patients after Femto-LASIK Keratorefractive Surgery
Purpose — to analyze the effectiveness of artificial tear drops HYLOPARIN-COMOD® in the complex medical support of the FemtoLASIK operation based on monitoring of clinical, functional and morphometric indicators of the eye surface’s condition. Patients and methods. The study included 25 patients (5...
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Ophthalmology Publishing Group
2020-06-01
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| Series: | Oftalʹmologiâ |
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| Online Access: | https://www.ophthalmojournal.com/opht/article/view/1207 |
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| author | I. E. Panova A. V. Titov D. R. Mirsaitova |
| author_facet | I. E. Panova A. V. Titov D. R. Mirsaitova |
| author_sort | I. E. Panova |
| collection | DOAJ |
| description | Purpose — to analyze the effectiveness of artificial tear drops HYLOPARIN-COMOD® in the complex medical support of the FemtoLASIK operation based on monitoring of clinical, functional and morphometric indicators of the eye surface’s condition. Patients and methods. The study included 25 patients (50 eyes) who underwent a keratorefractive surgery (Femto-LASIK) and were prescribed instillations of artificial tear drops HILOPARIN-COMOD®. To analyze the effectiveness of artificial tear drops HYLOPARIN-COMOD® in the complex medical support of the Femto-LASIK operation based on monitoring of clinical, functional and morphometric indicators of the eye surface’s condition: UCVA, BCVA, Schirmer’s II test, tear break-up time (Norn’s test), OCT pachymetry of the cornea and corneal flap. The treatment effectiveness was evaluated at 1 day, 1 week, 1 and 3 months after the surgery. Results. As a result of the treatment, the following refractive data were obtained: UCVA increased from 0.09 ± 0.02 to 0.94 ± 0.07 on the first day after surgery and to 0.96 ± 0.04 and 0.99 ± 0.07 to 1 and 3 months of follow-up, BCVA respectively, from 0.97 ± 0.04 to 0.94 ± 0.07, 0.97 ± 0.07 and 0.99 ± 0.07 after surgery. A faster restoration of the cornea and corneal valve was revealed, as evidenced by a decrease in their thickness already in the 1st week after surgery in comparison with the control group, where were more pronounced changes occur only by the 1st and 3rd month of observation (p ≤ 0.05). There was a significant increase in the basal secretion of the lacrimal gland (Schirmer’s II test) from 10.16 ± 1.33 to 11.66 ± 1.13 and 12.88 ± 0.96 µm by 1 and 3 months after surgical treatment, respectively (p ≤ 0.05). The Norn’s test increased from 10.89 ± 1.94 to 12.78 ± 1.59 and 13.83 ± 0.5 s to 1 and 3 months of treatment, respectively (p ≤ 0.05). Conclusion. The effectiveness of the HILOPARIN-COMOD® use in the correction of the dry eye syndrome after keratorefractive operations has been proven. The obtained results clearly demonstrate that the HILOPARIN-COMOD® preparation enhances not only the stability of the tear film, but also the restoration of the OCT morphometric parameters of the thickness of the cornea and corneal flap. |
| format | Article |
| id | doaj-art-c1e520c61c2d4848bd3e0f8e9b019c85 |
| institution | Kabale University |
| issn | 1816-5095 2500-0845 |
| language | Russian |
| publishDate | 2020-06-01 |
| publisher | Ophthalmology Publishing Group |
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| series | Oftalʹmologiâ |
| spelling | doaj-art-c1e520c61c2d4848bd3e0f8e9b019c852025-08-20T03:38:16ZrusOphthalmology Publishing GroupOftalʹmologiâ1816-50952500-08452020-06-0117227428010.18008/1816-5095-2020-2-274-280631Tear Replacement Therapy in Medical Support of Patients after Femto-LASIK Keratorefractive SurgeryI. E. Panova0A. V. Titov1D. R. Mirsaitova2St. Petersburg Branch of the S. Fyodorov Eye Microsurgery Federal State InstitutionSt. Petersburg Branch of the S. Fyodorov Eye Microsurgery Federal State InstitutionSt. Petersburg Branch of the S. Fyodorov Eye Microsurgery Federal State InstitutionPurpose — to analyze the effectiveness of artificial tear drops HYLOPARIN-COMOD® in the complex medical support of the FemtoLASIK operation based on monitoring of clinical, functional and morphometric indicators of the eye surface’s condition. Patients and methods. The study included 25 patients (50 eyes) who underwent a keratorefractive surgery (Femto-LASIK) and were prescribed instillations of artificial tear drops HILOPARIN-COMOD®. To analyze the effectiveness of artificial tear drops HYLOPARIN-COMOD® in the complex medical support of the Femto-LASIK operation based on monitoring of clinical, functional and morphometric indicators of the eye surface’s condition: UCVA, BCVA, Schirmer’s II test, tear break-up time (Norn’s test), OCT pachymetry of the cornea and corneal flap. The treatment effectiveness was evaluated at 1 day, 1 week, 1 and 3 months after the surgery. Results. As a result of the treatment, the following refractive data were obtained: UCVA increased from 0.09 ± 0.02 to 0.94 ± 0.07 on the first day after surgery and to 0.96 ± 0.04 and 0.99 ± 0.07 to 1 and 3 months of follow-up, BCVA respectively, from 0.97 ± 0.04 to 0.94 ± 0.07, 0.97 ± 0.07 and 0.99 ± 0.07 after surgery. A faster restoration of the cornea and corneal valve was revealed, as evidenced by a decrease in their thickness already in the 1st week after surgery in comparison with the control group, where were more pronounced changes occur only by the 1st and 3rd month of observation (p ≤ 0.05). There was a significant increase in the basal secretion of the lacrimal gland (Schirmer’s II test) from 10.16 ± 1.33 to 11.66 ± 1.13 and 12.88 ± 0.96 µm by 1 and 3 months after surgical treatment, respectively (p ≤ 0.05). The Norn’s test increased from 10.89 ± 1.94 to 12.78 ± 1.59 and 13.83 ± 0.5 s to 1 and 3 months of treatment, respectively (p ≤ 0.05). Conclusion. The effectiveness of the HILOPARIN-COMOD® use in the correction of the dry eye syndrome after keratorefractive operations has been proven. The obtained results clearly demonstrate that the HILOPARIN-COMOD® preparation enhances not only the stability of the tear film, but also the restoration of the OCT morphometric parameters of the thickness of the cornea and corneal flap.https://www.ophthalmojournal.com/opht/article/view/1207hyloparin-comod®keratorefractive surgeryfemto-lasikoct pachymetrydry eye syndrome (des) |
| spellingShingle | I. E. Panova A. V. Titov D. R. Mirsaitova Tear Replacement Therapy in Medical Support of Patients after Femto-LASIK Keratorefractive Surgery Oftalʹmologiâ hyloparin-comod® keratorefractive surgery femto-lasik oct pachymetry dry eye syndrome (des) |
| title | Tear Replacement Therapy in Medical Support of Patients after Femto-LASIK Keratorefractive Surgery |
| title_full | Tear Replacement Therapy in Medical Support of Patients after Femto-LASIK Keratorefractive Surgery |
| title_fullStr | Tear Replacement Therapy in Medical Support of Patients after Femto-LASIK Keratorefractive Surgery |
| title_full_unstemmed | Tear Replacement Therapy in Medical Support of Patients after Femto-LASIK Keratorefractive Surgery |
| title_short | Tear Replacement Therapy in Medical Support of Patients after Femto-LASIK Keratorefractive Surgery |
| title_sort | tear replacement therapy in medical support of patients after femto lasik keratorefractive surgery |
| topic | hyloparin-comod® keratorefractive surgery femto-lasik oct pachymetry dry eye syndrome (des) |
| url | https://www.ophthalmojournal.com/opht/article/view/1207 |
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