Pre-Descemet Corneal Dystrophy – Changes in Corneal Morphology in Confocal Microscopy
Purpose To identify and describe the in-vivo microstructural changes in the cornea of patients with pre-Descemet’s membrane corneal dystrophy. Methods Ten patients (20 eyes) were examined in the Laser Microsurgery Centre in Warsaw. The ophthalmic examination, including visual acuity and slit lamp b...
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| Format: | Article |
| Language: | English |
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Termedia Publishing House
2024-08-01
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| Series: | Okulistyka |
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| Online Access: | https://www.ophthalmologypoland.com.pl/Pre-Descemet-Corneal-Dystrophy-Changes-in-Corneal-Morphology-in-Confocal-Microscopy,191663,0,2.html |
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| _version_ | 1832589569111883776 |
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| author | Urszula Kołodziejska Anna K. Kurowska Jacek P. Szaflik Jerzy Szaflik |
| author_facet | Urszula Kołodziejska Anna K. Kurowska Jacek P. Szaflik Jerzy Szaflik |
| author_sort | Urszula Kołodziejska |
| collection | DOAJ |
| description | Purpose
To identify and describe the in-vivo microstructural changes in the cornea of patients with pre-Descemet’s membrane corneal dystrophy.
Methods
Ten patients (20 eyes) were examined in the Laser Microsurgery Centre in Warsaw. The ophthalmic examination, including visual acuity and slit lamp biomicroscopy, was carried out. Because of suspicion of corneal dystrophy, in vivo confocal microscopy of the cornea was also performed.
Results
Biomicroscopy revealed bilateral, dust-like fine opacities in the deep parts of the corneal stroma. Confocal microscopy showed pleomorphic structures (enlarged keratocytes) containing dense, hyperreflective, granular inclusions in the posterior stroma, next to the Descemet’s membrane. In 3 patients (6 eyes) punctate particles were seen extracellularly also in the mid stroma. Superficial and basal epithelial layers, anterior stroma and endothelium cells appeared normal.
Conclusions
1. In vivo confocal microscopy findings of cornea with pre-Descemet’s membrane dystrophy are characteristic. 2. In vivo confocal microscopy is a useful tool in diagnosing rare corneal dystrophies in cases where classical examination methods give inconclusive results. |
| format | Article |
| id | doaj-art-c1e3dd1233524d31aadd33bc5b810f71 |
| institution | Kabale University |
| issn | 1505-2753 1689-362X |
| language | English |
| publishDate | 2024-08-01 |
| publisher | Termedia Publishing House |
| record_format | Article |
| series | Okulistyka |
| spelling | doaj-art-c1e3dd1233524d31aadd33bc5b810f712025-01-24T12:40:43ZengTermedia Publishing HouseOkulistyka1505-27531689-362X2024-08-0127251010.5114/oku/191663191663Pre-Descemet Corneal Dystrophy – Changes in Corneal Morphology in Confocal MicroscopyUrszula Kołodziejska0Anna K. Kurowska1Jacek P. Szaflik2Jerzy Szaflik3Laser Eye Microsurgery Centre in WarsawDepartment of Ophthalmology Medical University of WarsawLaser Eye Microsurgery Centre in WarsawLaser Eye Microsurgery Centre in WarsawPurpose To identify and describe the in-vivo microstructural changes in the cornea of patients with pre-Descemet’s membrane corneal dystrophy. Methods Ten patients (20 eyes) were examined in the Laser Microsurgery Centre in Warsaw. The ophthalmic examination, including visual acuity and slit lamp biomicroscopy, was carried out. Because of suspicion of corneal dystrophy, in vivo confocal microscopy of the cornea was also performed. Results Biomicroscopy revealed bilateral, dust-like fine opacities in the deep parts of the corneal stroma. Confocal microscopy showed pleomorphic structures (enlarged keratocytes) containing dense, hyperreflective, granular inclusions in the posterior stroma, next to the Descemet’s membrane. In 3 patients (6 eyes) punctate particles were seen extracellularly also in the mid stroma. Superficial and basal epithelial layers, anterior stroma and endothelium cells appeared normal. Conclusions 1. In vivo confocal microscopy findings of cornea with pre-Descemet’s membrane dystrophy are characteristic. 2. In vivo confocal microscopy is a useful tool in diagnosing rare corneal dystrophies in cases where classical examination methods give inconclusive results.https://www.ophthalmologypoland.com.pl/Pre-Descemet-Corneal-Dystrophy-Changes-in-Corneal-Morphology-in-Confocal-Microscopy,191663,0,2.htmlpre-descemet corneal dystrophyin vivo confocal microscopy |
| spellingShingle | Urszula Kołodziejska Anna K. Kurowska Jacek P. Szaflik Jerzy Szaflik Pre-Descemet Corneal Dystrophy – Changes in Corneal Morphology in Confocal Microscopy Okulistyka pre-descemet corneal dystrophy in vivo confocal microscopy |
| title | Pre-Descemet Corneal Dystrophy – Changes in Corneal Morphology in Confocal Microscopy |
| title_full | Pre-Descemet Corneal Dystrophy – Changes in Corneal Morphology in Confocal Microscopy |
| title_fullStr | Pre-Descemet Corneal Dystrophy – Changes in Corneal Morphology in Confocal Microscopy |
| title_full_unstemmed | Pre-Descemet Corneal Dystrophy – Changes in Corneal Morphology in Confocal Microscopy |
| title_short | Pre-Descemet Corneal Dystrophy – Changes in Corneal Morphology in Confocal Microscopy |
| title_sort | pre descemet corneal dystrophy changes in corneal morphology in confocal microscopy |
| topic | pre-descemet corneal dystrophy in vivo confocal microscopy |
| url | https://www.ophthalmologypoland.com.pl/Pre-Descemet-Corneal-Dystrophy-Changes-in-Corneal-Morphology-in-Confocal-Microscopy,191663,0,2.html |
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