Effects of Idiopathic Restless Leg Syndrome on Intima-media Thickness of Carotid Artery: A Case Control Study

Purpose: Restless legs syndrome is claimed to be associated with a higher risk of cardiovascular diseases. Intima-media thickness has been reported to be the most valuable surrogate marker and predictor of atherosclerosis progression and upcoming cardiovascular diseases. In this study, we aimed to...

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Main Authors: Mohamad Ghazanfari Hashemi, Mahsa Vafaei Mastanabad, Maryam Alaei, Mohammad Ali Kaviani, Ali Asadifar, Rahim Momivand, Helia Helali, Maedeh Ghazanfari Hashemi, Marjan Gholami, Seyedeh Nooshin Miratashi Yazdi
Format: Article
Language:English
Published: Tehran University of Medical Sciences 2023-06-01
Series:Frontiers in Biomedical Technologies
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Online Access:https://fbt.tums.ac.ir/index.php/fbt/article/view/652
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author Mohamad Ghazanfari Hashemi
Mahsa Vafaei Mastanabad
Maryam Alaei
Mohammad Ali Kaviani
Ali Asadifar
Rahim Momivand
Helia Helali
Maedeh Ghazanfari Hashemi
Marjan Gholami
Seyedeh Nooshin Miratashi Yazdi
author_facet Mohamad Ghazanfari Hashemi
Mahsa Vafaei Mastanabad
Maryam Alaei
Mohammad Ali Kaviani
Ali Asadifar
Rahim Momivand
Helia Helali
Maedeh Ghazanfari Hashemi
Marjan Gholami
Seyedeh Nooshin Miratashi Yazdi
author_sort Mohamad Ghazanfari Hashemi
collection DOAJ
description Purpose: Restless legs syndrome is claimed to be associated with a higher risk of cardiovascular diseases. Intima-media thickness has been reported to be the most valuable surrogate marker and predictor of atherosclerosis progression and upcoming cardiovascular diseases. In this study, we aimed to evaluate the relationship between restless legs syndrome and intima-media thickness of the carotid artery. Materials and Methods: In this case-control study, a total of 23 patients with restless legs syndrome without other known risk factors of cardiovascular diseases were evaluated with regard to the intima-media thickness of the carotid artery by employing a high-resolution B-mode ultrasound study. The findings of the ultrasound study between the case and the control group were compared and statistically analyzed. Results: Intima-media thickness was revealed to be of a lower value in subjects with restless legs syndrome (0.79±0.10) compared to the control group (0.88±0.13). Also, our study showed that older age and the presence of hypertension directly correlates with intima-media thickness. Conclusion: It can be concluded that restless legs syndrome is associated with a lower intima-media thickness.
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series Frontiers in Biomedical Technologies
spelling doaj-art-c1daae60bb8741c2a20a124a460b8a352025-08-20T01:47:43ZengTehran University of Medical SciencesFrontiers in Biomedical Technologies2345-58372023-06-0111410.18502/fbt.v11i4.16510Effects of Idiopathic Restless Leg Syndrome on Intima-media Thickness of Carotid Artery: A Case Control StudyMohamad Ghazanfari Hashemi0Mahsa Vafaei Mastanabad1Maryam Alaei2Mohammad Ali Kaviani3Ali Asadifar4Rahim Momivand5Helia Helali6Maedeh Ghazanfari Hashemi7Marjan Gholami8Seyedeh Nooshin Miratashi Yazdi9Cancer institute, Department of Radiology, Tehran university of medical sciences, Tehran, IranNeurosurgery Department, Faculty of Medicine, Qazvin University of Medical Sciences, Qazvin, IranSchool of Medicine, Shahid Beheshti Medical University, Tehran, IranDepartment of Radiology, School of Medicine, Kerman University of Medical Sciences, Kerman, IranDepartment of Radiology, School of Medicine, Kerman University of Medical Sciences, Kerman, IranOral and Maxillofacial Radiology Department, Hamadan University of Medical Sciences, Hamadan, IranDepartment of Psychiatry, School of Medicine, Shahid Beheshti Medical University, Tehran, IranSchool of Medicine, Qazvin University of Medical Sciences, Qazvin, IranSchool of Pharmacy, Islamic Azad University Pharmaceutical Sciences Branch, Tehran, IranAdvanced Diagnostic and Interventional Radiology Research Center, Tehran University of Medical Sciences, Tehran, Iran Purpose: Restless legs syndrome is claimed to be associated with a higher risk of cardiovascular diseases. Intima-media thickness has been reported to be the most valuable surrogate marker and predictor of atherosclerosis progression and upcoming cardiovascular diseases. In this study, we aimed to evaluate the relationship between restless legs syndrome and intima-media thickness of the carotid artery. Materials and Methods: In this case-control study, a total of 23 patients with restless legs syndrome without other known risk factors of cardiovascular diseases were evaluated with regard to the intima-media thickness of the carotid artery by employing a high-resolution B-mode ultrasound study. The findings of the ultrasound study between the case and the control group were compared and statistically analyzed. Results: Intima-media thickness was revealed to be of a lower value in subjects with restless legs syndrome (0.79±0.10) compared to the control group (0.88±0.13). Also, our study showed that older age and the presence of hypertension directly correlates with intima-media thickness. Conclusion: It can be concluded that restless legs syndrome is associated with a lower intima-media thickness. https://fbt.tums.ac.ir/index.php/fbt/article/view/652Restless Legs SyndromeIntima-Media ThicknessCarotid Artery Ultrasound
spellingShingle Mohamad Ghazanfari Hashemi
Mahsa Vafaei Mastanabad
Maryam Alaei
Mohammad Ali Kaviani
Ali Asadifar
Rahim Momivand
Helia Helali
Maedeh Ghazanfari Hashemi
Marjan Gholami
Seyedeh Nooshin Miratashi Yazdi
Effects of Idiopathic Restless Leg Syndrome on Intima-media Thickness of Carotid Artery: A Case Control Study
Frontiers in Biomedical Technologies
Restless Legs Syndrome
Intima-Media Thickness
Carotid Artery Ultrasound
title Effects of Idiopathic Restless Leg Syndrome on Intima-media Thickness of Carotid Artery: A Case Control Study
title_full Effects of Idiopathic Restless Leg Syndrome on Intima-media Thickness of Carotid Artery: A Case Control Study
title_fullStr Effects of Idiopathic Restless Leg Syndrome on Intima-media Thickness of Carotid Artery: A Case Control Study
title_full_unstemmed Effects of Idiopathic Restless Leg Syndrome on Intima-media Thickness of Carotid Artery: A Case Control Study
title_short Effects of Idiopathic Restless Leg Syndrome on Intima-media Thickness of Carotid Artery: A Case Control Study
title_sort effects of idiopathic restless leg syndrome on intima media thickness of carotid artery a case control study
topic Restless Legs Syndrome
Intima-Media Thickness
Carotid Artery Ultrasound
url https://fbt.tums.ac.ir/index.php/fbt/article/view/652
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