Typhoid Fever due to Extended Spectrum β-Lactamase-Producing Salmonella enterica Serovar Typhi: A Case Report and Literature Review
Emergence of cephalosporin-resistant strains of Salmonella enterica serovar Typhi is a cause of concern in the management of enteric fever. Cephalosporin resistance in Salmonella species is mainly due to the production of extended-spectrum β-lactamases (ESBLs). The majority of ESBLs in Salmonella en...
Saved in:
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2018-01-01
|
| Series: | Case Reports in Infectious Diseases |
| Online Access: | http://dx.doi.org/10.1155/2018/4610246 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1849684442578157568 |
|---|---|
| author | Abdul Azeez Ahamed Riyaaz Vindya Perera Sabaratnam Sivakumaran Nelun de Silva |
| author_facet | Abdul Azeez Ahamed Riyaaz Vindya Perera Sabaratnam Sivakumaran Nelun de Silva |
| author_sort | Abdul Azeez Ahamed Riyaaz |
| collection | DOAJ |
| description | Emergence of cephalosporin-resistant strains of Salmonella enterica serovar Typhi is a cause of concern in the management of enteric fever. Cephalosporin resistance in Salmonella species is mainly due to the production of extended-spectrum β-lactamases (ESBLs). The majority of ESBLs in Salmonella enterica serovar Typhi are derivatives of the TEM, SHV, and CTX-M β-lactamase families. Of these, CTX-M appears to be predominant. This paper discusses the detection and molecular characterization of an ESBL-producing Salmonella enterica serovar Typhi strain isolated from a patient who was admitted to a private hospital in Sri Lanka. The three main types of β-lactamases such as TEM, SHV, and CTX-M were identified in this isolate. This case report from Sri Lanka contributes to the knowledge of the increasingly reported cases of typhoid fever due to Salmonella enterica serovar Typhi resistant to β-lactamase by ESBL production. |
| format | Article |
| id | doaj-art-c1d991cf13ee4b2b84cf252e250e762f |
| institution | DOAJ |
| issn | 2090-6625 2090-6633 |
| language | English |
| publishDate | 2018-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Infectious Diseases |
| spelling | doaj-art-c1d991cf13ee4b2b84cf252e250e762f2025-08-20T03:23:27ZengWileyCase Reports in Infectious Diseases2090-66252090-66332018-01-01201810.1155/2018/46102464610246Typhoid Fever due to Extended Spectrum β-Lactamase-Producing Salmonella enterica Serovar Typhi: A Case Report and Literature ReviewAbdul Azeez Ahamed Riyaaz0Vindya Perera1Sabaratnam Sivakumaran2Nelun de Silva3Department of Internal Medicine, Dr. Neville Fernando Teaching Hospital, Malabe, Sri LankaDepartment of Microbiology, Faculty of Medicine, South Asian Institute of Technology and Medicine, Malabe, Sri LankaDepartment of Internal Medicine, Dr. Neville Fernando Teaching Hospital, Malabe, Sri LankaDepartment of Microbiology, Faculty of Medicine, South Asian Institute of Technology and Medicine, Malabe, Sri LankaEmergence of cephalosporin-resistant strains of Salmonella enterica serovar Typhi is a cause of concern in the management of enteric fever. Cephalosporin resistance in Salmonella species is mainly due to the production of extended-spectrum β-lactamases (ESBLs). The majority of ESBLs in Salmonella enterica serovar Typhi are derivatives of the TEM, SHV, and CTX-M β-lactamase families. Of these, CTX-M appears to be predominant. This paper discusses the detection and molecular characterization of an ESBL-producing Salmonella enterica serovar Typhi strain isolated from a patient who was admitted to a private hospital in Sri Lanka. The three main types of β-lactamases such as TEM, SHV, and CTX-M were identified in this isolate. This case report from Sri Lanka contributes to the knowledge of the increasingly reported cases of typhoid fever due to Salmonella enterica serovar Typhi resistant to β-lactamase by ESBL production.http://dx.doi.org/10.1155/2018/4610246 |
| spellingShingle | Abdul Azeez Ahamed Riyaaz Vindya Perera Sabaratnam Sivakumaran Nelun de Silva Typhoid Fever due to Extended Spectrum β-Lactamase-Producing Salmonella enterica Serovar Typhi: A Case Report and Literature Review Case Reports in Infectious Diseases |
| title | Typhoid Fever due to Extended Spectrum β-Lactamase-Producing Salmonella enterica Serovar Typhi: A Case Report and Literature Review |
| title_full | Typhoid Fever due to Extended Spectrum β-Lactamase-Producing Salmonella enterica Serovar Typhi: A Case Report and Literature Review |
| title_fullStr | Typhoid Fever due to Extended Spectrum β-Lactamase-Producing Salmonella enterica Serovar Typhi: A Case Report and Literature Review |
| title_full_unstemmed | Typhoid Fever due to Extended Spectrum β-Lactamase-Producing Salmonella enterica Serovar Typhi: A Case Report and Literature Review |
| title_short | Typhoid Fever due to Extended Spectrum β-Lactamase-Producing Salmonella enterica Serovar Typhi: A Case Report and Literature Review |
| title_sort | typhoid fever due to extended spectrum β lactamase producing salmonella enterica serovar typhi a case report and literature review |
| url | http://dx.doi.org/10.1155/2018/4610246 |
| work_keys_str_mv | AT abdulazeezahamedriyaaz typhoidfeverduetoextendedspectrumblactamaseproducingsalmonellaentericaserovartyphiacasereportandliteraturereview AT vindyaperera typhoidfeverduetoextendedspectrumblactamaseproducingsalmonellaentericaserovartyphiacasereportandliteraturereview AT sabaratnamsivakumaran typhoidfeverduetoextendedspectrumblactamaseproducingsalmonellaentericaserovartyphiacasereportandliteraturereview AT nelundesilva typhoidfeverduetoextendedspectrumblactamaseproducingsalmonellaentericaserovartyphiacasereportandliteraturereview |