Antiarrhythmic potentials of irisin in ischemia/reperfusion injury of diabetic rats through modulating mitochondria-endoplasmic reticulum interaction and inhibiting pyroptosis

Antiarrhythmic potentials of irisin in ischemia/reperfusion injury of diabetic rats through modulating mitochondria-endoplasmic reticulum interaction and inhibiting pyroptosis

Objective(s): Myocardial arrhythmia is a major complication of ischemia-reperfusion (I/R) injury in patients with diabetes. Irisin has significant cardioprotective effects, while its role in the pathophysiology of I/R injury-induced myocardial arrhythmia in the presence of diabetes is not well ident...

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Bibliographic Details
Main Authors: Xiaona Zhang, Kai Jing, Wei Ma, Jin Wang
Format: Article
Language:English
Published: Mashhad University of Medical Sciences 2024-11-01
Series:Iranian Journal of Basic Medical Sciences
Subjects:
arrhythmia
cardioprotection
diabetes
inflammation
pyroptosis
reperfusion
Online Access:https://ijbms.mums.ac.ir/article_24698_ea1812d82ef5472857089282eb5df6c5.pdf
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