Complicated skin and soft tissue infection with Mycobacterium fortuitum following excision of a sebaceous cyst in Taiwan
Mycobacterium fortuitum group (M. fortuitum), also known as rapidly growing Mycobacteria, can cause pyogenic infections in human beings, most commonly in immunocompromised patients. Herein, we present a 40-year-old immunocompetent male patient who underwent planned excision of a sebaceous cyst in th...
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The Journal of Infection in Developing Countries
2016-12-01
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| Series: | Journal of Infection in Developing Countries |
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| Online Access: | https://jidc.org/index.php/journal/article/view/7356 |
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| author | Shih-Chen Tsai Li-Hsin Chen Hsien-Hua Liao Chih-Yu Chiang Wea-Lung Lin Shiuan-Chih Chen Shih-Ming Tsao Hung-Chang Hung Yuan-Ti Lee |
| author_facet | Shih-Chen Tsai Li-Hsin Chen Hsien-Hua Liao Chih-Yu Chiang Wea-Lung Lin Shiuan-Chih Chen Shih-Ming Tsao Hung-Chang Hung Yuan-Ti Lee |
| author_sort | Shih-Chen Tsai |
| collection | DOAJ |
| description | Mycobacterium fortuitum group (M. fortuitum), also known as rapidly growing Mycobacteria, can cause pyogenic infections in human beings, most commonly in immunocompromised patients. Herein, we present a 40-year-old immunocompetent male patient who underwent planned excision of a sebaceous cyst in the abdominal wall. He suffered from tender erythematous lesions with purulent discharge around the healing wound that developed 2 weeks after surgery. Gram stain, bacterial and fungal culture results of the wound were negative. A diagnosis of non-tuberculous mycobacteria was made from a wound culture from the area of operative debridement, which was subsequently confirmed to be M. fortuitum group using PCR-restriction fragment length polymorphism analysis of the hsp65 gene. The patient received 4 weeks of parenteral imipenem/cilastatin 500 mg every 6 hours and amikacin 500 mg every 12 hours, plus oral clarithromycin 500 mg twice daily, and the wound recovered completely. He was discharged and followed up regularly at our outpatient clinic, and continued taking oral ciprofloxacin and clarithromycin 500 mg twice daily for 6 months. This case highlights the importance of strict aseptic precautions even during minor procedures, and also the characteristics of M. fortuitum infections in immunocompetent patients, which usually develop as localized postsurgical wound infections. We also share our experience in successfully treating a M. fortuitum complicated skin and soft tissue infection.
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| format | Article |
| id | doaj-art-c1c4826a8d8d4bd786a959ce84f9ceae |
| institution | OA Journals |
| issn | 1972-2680 |
| language | English |
| publishDate | 2016-12-01 |
| publisher | The Journal of Infection in Developing Countries |
| record_format | Article |
| series | Journal of Infection in Developing Countries |
| spelling | doaj-art-c1c4826a8d8d4bd786a959ce84f9ceae2025-08-20T02:14:14ZengThe Journal of Infection in Developing CountriesJournal of Infection in Developing Countries1972-26802016-12-01101210.3855/jidc.7356Complicated skin and soft tissue infection with Mycobacterium fortuitum following excision of a sebaceous cyst in TaiwanShih-Chen Tsai0Li-Hsin Chen1Hsien-Hua Liao2Chih-Yu Chiang3Wea-Lung Lin4Shiuan-Chih Chen5Shih-Ming Tsao6Hung-Chang Hung7Yuan-Ti Lee8Chung Shan Medical University, Taichung, Taiwan, ROCChung Shan Medical University, Taichung, Taiwan, ROCChung Shan Medical University, Taichung, Taiwan, ROCChung Shan Medical University, Taichung, Taiwan, ROCChung Shan Medical University, Taichung, Taiwan, ROCChung Shan Medical University, Taichung, Taiwan, ROCChung Shan Medical University, Taichung, Taiwan, ROCChung Shan Medical University, Taichung, Taiwan, ROCChung Shan Medical University, Taichung, Taiwan, ROCMycobacterium fortuitum group (M. fortuitum), also known as rapidly growing Mycobacteria, can cause pyogenic infections in human beings, most commonly in immunocompromised patients. Herein, we present a 40-year-old immunocompetent male patient who underwent planned excision of a sebaceous cyst in the abdominal wall. He suffered from tender erythematous lesions with purulent discharge around the healing wound that developed 2 weeks after surgery. Gram stain, bacterial and fungal culture results of the wound were negative. A diagnosis of non-tuberculous mycobacteria was made from a wound culture from the area of operative debridement, which was subsequently confirmed to be M. fortuitum group using PCR-restriction fragment length polymorphism analysis of the hsp65 gene. The patient received 4 weeks of parenteral imipenem/cilastatin 500 mg every 6 hours and amikacin 500 mg every 12 hours, plus oral clarithromycin 500 mg twice daily, and the wound recovered completely. He was discharged and followed up regularly at our outpatient clinic, and continued taking oral ciprofloxacin and clarithromycin 500 mg twice daily for 6 months. This case highlights the importance of strict aseptic precautions even during minor procedures, and also the characteristics of M. fortuitum infections in immunocompetent patients, which usually develop as localized postsurgical wound infections. We also share our experience in successfully treating a M. fortuitum complicated skin and soft tissue infection. https://jidc.org/index.php/journal/article/view/7356Mycobacterium fortuitumnon-tuberculous mycobacteriacomplicated skin and soft tissue infectionsurgical site infectionantimicrobial treatment |
| spellingShingle | Shih-Chen Tsai Li-Hsin Chen Hsien-Hua Liao Chih-Yu Chiang Wea-Lung Lin Shiuan-Chih Chen Shih-Ming Tsao Hung-Chang Hung Yuan-Ti Lee Complicated skin and soft tissue infection with Mycobacterium fortuitum following excision of a sebaceous cyst in Taiwan Journal of Infection in Developing Countries Mycobacterium fortuitum non-tuberculous mycobacteria complicated skin and soft tissue infection surgical site infection antimicrobial treatment |
| title | Complicated skin and soft tissue infection with Mycobacterium fortuitum following excision of a sebaceous cyst in Taiwan |
| title_full | Complicated skin and soft tissue infection with Mycobacterium fortuitum following excision of a sebaceous cyst in Taiwan |
| title_fullStr | Complicated skin and soft tissue infection with Mycobacterium fortuitum following excision of a sebaceous cyst in Taiwan |
| title_full_unstemmed | Complicated skin and soft tissue infection with Mycobacterium fortuitum following excision of a sebaceous cyst in Taiwan |
| title_short | Complicated skin and soft tissue infection with Mycobacterium fortuitum following excision of a sebaceous cyst in Taiwan |
| title_sort | complicated skin and soft tissue infection with mycobacterium fortuitum following excision of a sebaceous cyst in taiwan |
| topic | Mycobacterium fortuitum non-tuberculous mycobacteria complicated skin and soft tissue infection surgical site infection antimicrobial treatment |
| url | https://jidc.org/index.php/journal/article/view/7356 |
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