Advances in Graphene Field Effect Transistors (FETs) for Amine Neurotransmitter Sensing
Amine neurotransmitters (NTs) are crucial in the central nervous system, and dysregulation in their levels is implicated in a spectrum of neurological disorders. Thus, a precise and timely assessment of their concentrations is critical for early diagnosis and treatment efficacy monitoring. Graphene-...
Saved in:
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2024-11-01
|
| Series: | Applied Sciences |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2076-3417/14/22/10109 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1850267671884464128 |
|---|---|
| author | Elmira Alimohammadzadeh John Hedley |
| author_facet | Elmira Alimohammadzadeh John Hedley |
| author_sort | Elmira Alimohammadzadeh |
| collection | DOAJ |
| description | Amine neurotransmitters (NTs) are crucial in the central nervous system, and dysregulation in their levels is implicated in a spectrum of neurological disorders. Thus, a precise and timely assessment of their concentrations is critical for early diagnosis and treatment efficacy monitoring. Graphene-based field effect transistors (GFETs) have become a ground-breaking instrument in the detection of these NTs because of their exceptional electrical characteristics and adaptability. This paper summarises the significant advancements in GFET biosensors in amine NT detection and highlights developments in the selectivity, sensitivity, and limit of detection (LOD) attained by selecting various graphene materials and functionalisation approaches. |
| format | Article |
| id | doaj-art-c1c44f1ea650428f8c7c2d79cbded25d |
| institution | OA Journals |
| issn | 2076-3417 |
| language | English |
| publishDate | 2024-11-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Applied Sciences |
| spelling | doaj-art-c1c44f1ea650428f8c7c2d79cbded25d2025-08-20T01:53:42ZengMDPI AGApplied Sciences2076-34172024-11-0114221010910.3390/app142210109Advances in Graphene Field Effect Transistors (FETs) for Amine Neurotransmitter SensingElmira Alimohammadzadeh0John Hedley1School of Engineering, Newcastle University, Newcastle Upon Tyne NE1 7RU, UKSchool of Engineering, Newcastle University, Newcastle Upon Tyne NE1 7RU, UKAmine neurotransmitters (NTs) are crucial in the central nervous system, and dysregulation in their levels is implicated in a spectrum of neurological disorders. Thus, a precise and timely assessment of their concentrations is critical for early diagnosis and treatment efficacy monitoring. Graphene-based field effect transistors (GFETs) have become a ground-breaking instrument in the detection of these NTs because of their exceptional electrical characteristics and adaptability. This paper summarises the significant advancements in GFET biosensors in amine NT detection and highlights developments in the selectivity, sensitivity, and limit of detection (LOD) attained by selecting various graphene materials and functionalisation approaches.https://www.mdpi.com/2076-3417/14/22/10109grapheneGFETbiosensorneurotransmitters |
| spellingShingle | Elmira Alimohammadzadeh John Hedley Advances in Graphene Field Effect Transistors (FETs) for Amine Neurotransmitter Sensing Applied Sciences graphene GFET biosensor neurotransmitters |
| title | Advances in Graphene Field Effect Transistors (FETs) for Amine Neurotransmitter Sensing |
| title_full | Advances in Graphene Field Effect Transistors (FETs) for Amine Neurotransmitter Sensing |
| title_fullStr | Advances in Graphene Field Effect Transistors (FETs) for Amine Neurotransmitter Sensing |
| title_full_unstemmed | Advances in Graphene Field Effect Transistors (FETs) for Amine Neurotransmitter Sensing |
| title_short | Advances in Graphene Field Effect Transistors (FETs) for Amine Neurotransmitter Sensing |
| title_sort | advances in graphene field effect transistors fets for amine neurotransmitter sensing |
| topic | graphene GFET biosensor neurotransmitters |
| url | https://www.mdpi.com/2076-3417/14/22/10109 |
| work_keys_str_mv | AT elmiraalimohammadzadeh advancesingraphenefieldeffecttransistorsfetsforamineneurotransmittersensing AT johnhedley advancesingraphenefieldeffecttransistorsfetsforamineneurotransmittersensing |