Targeted activation of ErbB4 receptor ameliorates neuronal deficits and neuroinflammation in a food-borne polystyrene microplastic exposed mouse model

Targeted activation of ErbB4 receptor ameliorates neuronal deficits and neuroinflammation in a food-borne polystyrene microplastic exposed mouse model

Abstract The impact of polystyrene microplastics (PS-MPs) on the nervous system has been documented in the literature. Numerous studies have demonstrated that the activation of the epidermal growth factor receptor 4 (ErbB4) is crucial in neuronal injury and regeneration processes. This study investi...

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Bibliographic Details
Main Authors: Chong Liu, Yan Zhao, Wei Zhang, Ji-Ji Dao, Qian Li, Jia Huang, Zhen-Feng Li, Yu-Ke Ma, Chen-Meng Qiao, Chun Cui, Shuang-Xi Chen, Li Yu, Yan-Qin Shen, Wei-Jiang Zhao
Format: Article
Language:English
Published: BMC 2025-03-01
Series:Journal of Neuroinflammation
Subjects:
PS-MPs
Neuronal damage
Neuroinflammation
ErbB4 receptor
Small molecule
Mitochondrial damage
Online Access:https://doi.org/10.1186/s12974-025-03406-6
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