Neurodevelopmental, cognitive and motor function: Practice recommendations in pediatric intestinal failure and transplantation- position statement of the International Intestinal Rehabilitation and Transplant Association allied health committee

Background: The objective of this position statement was to provide evidence-based and expert-informed recommendations for the assessment and treatment of neurodevelopment in children with intestinal failure and those undergoing intestinal transplant. Material and methods: A literature review was co...

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Main Authors: Stephanie So, Catherine Patterson, Taru Palsa, Jemma Mears, Bianca C. Bondi, Sydney Dempster, Christina Belza
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:Intestinal Failure
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Online Access:http://www.sciencedirect.com/science/article/pii/S2950456225000272
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author Stephanie So
Catherine Patterson
Taru Palsa
Jemma Mears
Bianca C. Bondi
Sydney Dempster
Christina Belza
author_facet Stephanie So
Catherine Patterson
Taru Palsa
Jemma Mears
Bianca C. Bondi
Sydney Dempster
Christina Belza
author_sort Stephanie So
collection DOAJ
description Background: The objective of this position statement was to provide evidence-based and expert-informed recommendations for the assessment and treatment of neurodevelopment in children with intestinal failure and those undergoing intestinal transplant. Material and methods: A literature review was conducted to identify and review research articles from 2000 to 2023 that reported on neurodevelopmental, neurocognitive and motor outcomes in children (0–18 years) with intestinal failure or intestinal transplant. Key recommendations to address these outcomes were made based on scientific evidence and expert-informed opinion Results: The impact of intestinal failure and transplant on developmental outcomes was established, along with key risk factors related to the disease that may result in poorer outcomes. The involvement of rehabilitation specialists was recommended as part of the multidisciplinary intestinal care team to provide assessment and treatment across all developmental domains from infancy onwards. Care teams should provide close follow-up which may include screening during out-patient clinic follow up, along with timely community referrals to address developmental delays. Children undergoing intestinal or multi-visceral transplant require assessment and treatment both pre and post-transplant to maximize developmental outcomes. Conclusions: This position paper reviews available literature related to developmental outcomes in intestinal failure and transplant, delineating risk factors which may contribute to poorer outcomes. It lays the foundation for tangible steps to assist intestinal care teams in advocating for the services of rehabilitation team members to provide ongoing assessment and treatment to optimize clinical outcomes.
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publishDate 2025-01-01
publisher Elsevier
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series Intestinal Failure
spelling doaj-art-c1b79fc6737840a0b139115f4da5be2f2025-08-20T03:31:53ZengElsevierIntestinal Failure2950-45622025-01-01510006210.1016/j.intf.2025.100062Neurodevelopmental, cognitive and motor function: Practice recommendations in pediatric intestinal failure and transplantation- position statement of the International Intestinal Rehabilitation and Transplant Association allied health committeeStephanie So0Catherine Patterson1Taru Palsa2Jemma Mears3Bianca C. Bondi4Sydney Dempster5Christina Belza6Department of Rehabilitation Services, The Hospital for Sick Children, Toronto, Ontario, Canada; Department of Physical Therapy, Temerty Faculty of Medicine, University of Toronto, Canada; Group for Improvement of Intestinal Function and Treatment (GIFT), The Hospital for Sick Children, Toronto, Ontario, Canada; Transplant and Regenerative Medicine Centre, The Hospital for Sick Children, Toronto, Ontario, Canada; Correspondence to: Department of Rehabilitation Services, The Hospital for Sick Children, 555 University Ave, Toronto, Ontario M5G 1X8, Canada.Department of Rehabilitation Services, The Hospital for Sick Children, Toronto, Ontario, Canada; Department of Physical Therapy, Temerty Faculty of Medicine, University of Toronto, Canada; Group for Improvement of Intestinal Function and Treatment (GIFT), The Hospital for Sick Children, Toronto, Ontario, Canada; Transplant and Regenerative Medicine Centre, The Hospital for Sick Children, Toronto, Ontario, CanadaHelsinki University Hospital, New Children’s Hospital, Helsinki, FinlandPhysiotherapy Department, Birmingham Children's Hospital, United KingdomDepartment of Psychology, The Hospital for Sick Children, Toronto, Ontario, CanadaDepartment of Physical Therapy, Temerty Faculty of Medicine, University of Toronto, CanadaGroup for Improvement of Intestinal Function and Treatment (GIFT), The Hospital for Sick Children, Toronto, Ontario, Canada; Transplant and Regenerative Medicine Centre, The Hospital for Sick Children, Toronto, Ontario, Canada; Research Institute, The Hospital for Sick Children, Toronto, Ontario, CanadaBackground: The objective of this position statement was to provide evidence-based and expert-informed recommendations for the assessment and treatment of neurodevelopment in children with intestinal failure and those undergoing intestinal transplant. Material and methods: A literature review was conducted to identify and review research articles from 2000 to 2023 that reported on neurodevelopmental, neurocognitive and motor outcomes in children (0–18 years) with intestinal failure or intestinal transplant. Key recommendations to address these outcomes were made based on scientific evidence and expert-informed opinion Results: The impact of intestinal failure and transplant on developmental outcomes was established, along with key risk factors related to the disease that may result in poorer outcomes. The involvement of rehabilitation specialists was recommended as part of the multidisciplinary intestinal care team to provide assessment and treatment across all developmental domains from infancy onwards. Care teams should provide close follow-up which may include screening during out-patient clinic follow up, along with timely community referrals to address developmental delays. Children undergoing intestinal or multi-visceral transplant require assessment and treatment both pre and post-transplant to maximize developmental outcomes. Conclusions: This position paper reviews available literature related to developmental outcomes in intestinal failure and transplant, delineating risk factors which may contribute to poorer outcomes. It lays the foundation for tangible steps to assist intestinal care teams in advocating for the services of rehabilitation team members to provide ongoing assessment and treatment to optimize clinical outcomes.http://www.sciencedirect.com/science/article/pii/S2950456225000272Intestinal failureIntestinal transplantNeurodevelopmentNeurocognitionMotor development
spellingShingle Stephanie So
Catherine Patterson
Taru Palsa
Jemma Mears
Bianca C. Bondi
Sydney Dempster
Christina Belza
Neurodevelopmental, cognitive and motor function: Practice recommendations in pediatric intestinal failure and transplantation- position statement of the International Intestinal Rehabilitation and Transplant Association allied health committee
Intestinal Failure
Intestinal failure
Intestinal transplant
Neurodevelopment
Neurocognition
Motor development
title Neurodevelopmental, cognitive and motor function: Practice recommendations in pediatric intestinal failure and transplantation- position statement of the International Intestinal Rehabilitation and Transplant Association allied health committee
title_full Neurodevelopmental, cognitive and motor function: Practice recommendations in pediatric intestinal failure and transplantation- position statement of the International Intestinal Rehabilitation and Transplant Association allied health committee
title_fullStr Neurodevelopmental, cognitive and motor function: Practice recommendations in pediatric intestinal failure and transplantation- position statement of the International Intestinal Rehabilitation and Transplant Association allied health committee
title_full_unstemmed Neurodevelopmental, cognitive and motor function: Practice recommendations in pediatric intestinal failure and transplantation- position statement of the International Intestinal Rehabilitation and Transplant Association allied health committee
title_short Neurodevelopmental, cognitive and motor function: Practice recommendations in pediatric intestinal failure and transplantation- position statement of the International Intestinal Rehabilitation and Transplant Association allied health committee
title_sort neurodevelopmental cognitive and motor function practice recommendations in pediatric intestinal failure and transplantation position statement of the international intestinal rehabilitation and transplant association allied health committee
topic Intestinal failure
Intestinal transplant
Neurodevelopment
Neurocognition
Motor development
url http://www.sciencedirect.com/science/article/pii/S2950456225000272
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