The Histamine Pathway is a Target to Treat Hepatic Experimental Erythropoietic ProtoporphyriaSummary
Background & Aims: Erythropoietic protoporphyria (EPP) is caused by mutations in ferrochelatase, which inserts iron into protoporphyrin-IX (PP-IX) to generate heme. EPP is characterized by PP-IX accumulation, skin photosensitivity, cholestasis, and end-stage liver disease. Despite available...
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| Main Authors: | Ning Kuo, Pei Li, Juliana Bragazzi Cunha, Lu Chen, Jordan A. Shavit, M. Bishr Omary |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2025-01-01
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| Series: | Cellular and Molecular Gastroenterology and Hepatology |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2352345X25000049 |
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