Rising incidence of recreational ketamine use: Clinical cases and management in emergency settings
The recreational use of ketamine has risen significantly in the Netherlands, particularly among young adults in nightlife settings. This trend has been accompanied by an increase in first aid incidents involving ketamine, often in combination with other substances such as alcohol or MDMA, leading to...
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| Format: | Article |
| Language: | English |
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Elsevier
2025-06-01
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| Series: | Toxicology Reports |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2214750025000587 |
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| author | Sabrina Marongiu Maarten van Eijk Femke M.J. Gresnigt Esther A. Croes Eric J.F. Franssen |
| author_facet | Sabrina Marongiu Maarten van Eijk Femke M.J. Gresnigt Esther A. Croes Eric J.F. Franssen |
| author_sort | Sabrina Marongiu |
| collection | DOAJ |
| description | The recreational use of ketamine has risen significantly in the Netherlands, particularly among young adults in nightlife settings. This trend has been accompanied by an increase in first aid incidents involving ketamine, often in combination with other substances such as alcohol or MDMA, leading to heightened toxicity. Acute intoxication with ketamine manifests through symptoms like agitation, hallucinations, nausea, tachycardia, and hypertension, while frequent use is associated with long-term complications, including ketamine-induced uropathy. Although ketamine is not currently included in standard toxicological screenings, its detection can aid in diagnosing mixed intoxications, excluding alternative causes, and facilitating referral to follow-up care. Routine inclusion of ketamine in toxicological screening could improve diagnostic precision and better address the health risks associated with its growing prevalence. |
| format | Article |
| id | doaj-art-c1b684153a4749aa8da84b3822e0b2b2 |
| institution | Kabale University |
| issn | 2214-7500 |
| language | English |
| publishDate | 2025-06-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Toxicology Reports |
| spelling | doaj-art-c1b684153a4749aa8da84b3822e0b2b22025-02-07T04:47:37ZengElsevierToxicology Reports2214-75002025-06-0114101940Rising incidence of recreational ketamine use: Clinical cases and management in emergency settingsSabrina Marongiu0Maarten van Eijk1Femke M.J. Gresnigt2Esther A. Croes3Eric J.F. Franssen4Department of Clinical Pharmacy, OLVG hospital, Amsterdam, the NetherlandsDepartment of Medical Oncology and Clinical Pharmacology, The Netherlands Cancer Institute - Antoni van Leeuwenhoek hospital, Amsterdam, the NetherlandsDepartment of Emergency Care, OLVG hospital, Amsterdam, the Netherlands; Department of Clinical Toxicology, National Poisoning Information Center, UMC Utrecht, Utrecht, the NetherlandsTrimbos Institute, Utrecht, the NetherlandsDepartment of Clinical Pharmacy, OLVG hospital, Amsterdam, the Netherlands; Correspondence to: Jan Tooropstraat 164, Amsterdam 1061 AE, the Netherlands.The recreational use of ketamine has risen significantly in the Netherlands, particularly among young adults in nightlife settings. This trend has been accompanied by an increase in first aid incidents involving ketamine, often in combination with other substances such as alcohol or MDMA, leading to heightened toxicity. Acute intoxication with ketamine manifests through symptoms like agitation, hallucinations, nausea, tachycardia, and hypertension, while frequent use is associated with long-term complications, including ketamine-induced uropathy. Although ketamine is not currently included in standard toxicological screenings, its detection can aid in diagnosing mixed intoxications, excluding alternative causes, and facilitating referral to follow-up care. Routine inclusion of ketamine in toxicological screening could improve diagnostic precision and better address the health risks associated with its growing prevalence.http://www.sciencedirect.com/science/article/pii/S2214750025000587KetamineEmergency medicineIntoxicationMixed intoxicationKetamine-induced uropathyDrugs-of-abuse |
| spellingShingle | Sabrina Marongiu Maarten van Eijk Femke M.J. Gresnigt Esther A. Croes Eric J.F. Franssen Rising incidence of recreational ketamine use: Clinical cases and management in emergency settings Toxicology Reports Ketamine Emergency medicine Intoxication Mixed intoxication Ketamine-induced uropathy Drugs-of-abuse |
| title | Rising incidence of recreational ketamine use: Clinical cases and management in emergency settings |
| title_full | Rising incidence of recreational ketamine use: Clinical cases and management in emergency settings |
| title_fullStr | Rising incidence of recreational ketamine use: Clinical cases and management in emergency settings |
| title_full_unstemmed | Rising incidence of recreational ketamine use: Clinical cases and management in emergency settings |
| title_short | Rising incidence of recreational ketamine use: Clinical cases and management in emergency settings |
| title_sort | rising incidence of recreational ketamine use clinical cases and management in emergency settings |
| topic | Ketamine Emergency medicine Intoxication Mixed intoxication Ketamine-induced uropathy Drugs-of-abuse |
| url | http://www.sciencedirect.com/science/article/pii/S2214750025000587 |
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