Rehabilitation improves the effectiveness of nusinersen in children with type 2 spinal muscular atrophy: pNF-H and muscle MRI as potential biomarkers

Rehabilitation improves the effectiveness of nusinersen in children with type 2 spinal muscular atrophy: pNF-H and muscle MRI as potential biomarkers

IntroductionRehabilitation therapy is an important approach for spinal muscular atrophy (SMA) management. Currently, rare articles introduce that the combination of nusinersen and rehabilitation yields better results in SMA patients compared to using nusinersen alone. The present study examined whet...

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Bibliographic Details
Main Authors: Yifan Sun, Wei Li, Xin Cui, Yang Li, Xiucheng Gao, Dalin Fu, Xiaoke Zhao, Tong Cao, Min Zhu
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-04-01
Series:Frontiers in Neurology
Subjects:
type-2 spinal muscular atrophy
muscle magnetic resonance imaging
nusinersen
rehabilitation therapy
phosphorylated neurofilament heavy chain
Online Access:https://www.frontiersin.org/articles/10.3389/fneur.2025.1549587/full
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