PHENOTYPIC PLASTICITY OF BRONCHOPULMONARY EPITHELIUM IN THE DEVELOPMENT OF PULMONARY OSSIFICATION IN MINERS (ANALYTICAL REVIEW, ANALYSIS OF CLINICAL CASES, SUBSTANTIATION OF THE RESEARCH METHOD)
Osteoplastic pulmonopathy is an extremely rare but serious complication of occupational lung diseases, characterized by the formation of bone tissue in the lung parenchyma. This review is dedicated to studying the cellular mechanisms of osteoplastic pulmonopathy development in miners exposed to long...
Saved in:
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | Russian |
| Published: |
The Publishing House Medicine and Enlightenment
2024-12-01
|
| Series: | Медицина в Кузбассе |
| Subjects: | |
| Online Access: | https://mednauki.ru/index.php/MK/article/view/1173 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1849693251977609216 |
|---|---|
| author | Олег Иванович Бондарев Мария Сергеевна Бугаева Евгения Викторовна Уланова |
| author_facet | Олег Иванович Бондарев Мария Сергеевна Бугаева Евгения Викторовна Уланова |
| author_sort | Олег Иванович Бондарев |
| collection | DOAJ |
| description | Osteoplastic pulmonopathy is an extremely rare but serious complication of occupational lung diseases, characterized by the formation of bone tissue in the lung parenchyma. This review is dedicated to studying the cellular mechanisms of osteoplastic pulmonopathy development in miners exposed to long-term effects of coal-rock dust, with particular attention to the role of phenotypic plasticity of the bronchopulmonary epithelium. This is a specific, relevant topic, taking into account the peculiarities of professional risks in mining activities.
Objective of the review was to present current data on the extremely rare pathology of osteoplastic pulmonopathy as one of the variants that may be associated with the occupational pathology of miners.
Conclusion. Literature data and our own observation, combined with the absence of radiological signs specific to osteoplastic pulmonopathy and the possibility of its clinically asymptomatic course, give reason to assume a wider prevalence of osteoplastic pulmonopathy, which in workers of dust professions may occur under the guise of lung calcification, being, in fact, a form of pneumoconiosis. |
| format | Article |
| id | doaj-art-c19d41d379d348c292197f49be5fd397 |
| institution | DOAJ |
| issn | 1819-0901 2588-0411 |
| language | Russian |
| publishDate | 2024-12-01 |
| publisher | The Publishing House Medicine and Enlightenment |
| record_format | Article |
| series | Медицина в Кузбассе |
| spelling | doaj-art-c19d41d379d348c292197f49be5fd3972025-08-20T03:20:29ZrusThe Publishing House Medicine and EnlightenmentМедицина в Кузбассе1819-09012588-04112024-12-0123485891008PHENOTYPIC PLASTICITY OF BRONCHOPULMONARY EPITHELIUM IN THE DEVELOPMENT OF PULMONARY OSSIFICATION IN MINERS (ANALYTICAL REVIEW, ANALYSIS OF CLINICAL CASES, SUBSTANTIATION OF THE RESEARCH METHOD)Олег Иванович Бондарев0Мария Сергеевна Бугаева1Евгения Викторовна Уланова2Новокузнецкий государственный институт усовершенствования врачей – филиал ФГБОУ ДПО РМАНПО Минздрава РоссииФГБНУ НИИ КПГПЗ, г. НовокузнецкФГБНУ НИИ КПГПЗ, г. НовокузнецкOsteoplastic pulmonopathy is an extremely rare but serious complication of occupational lung diseases, characterized by the formation of bone tissue in the lung parenchyma. This review is dedicated to studying the cellular mechanisms of osteoplastic pulmonopathy development in miners exposed to long-term effects of coal-rock dust, with particular attention to the role of phenotypic plasticity of the bronchopulmonary epithelium. This is a specific, relevant topic, taking into account the peculiarities of professional risks in mining activities. Objective of the review was to present current data on the extremely rare pathology of osteoplastic pulmonopathy as one of the variants that may be associated with the occupational pathology of miners. Conclusion. Literature data and our own observation, combined with the absence of radiological signs specific to osteoplastic pulmonopathy and the possibility of its clinically asymptomatic course, give reason to assume a wider prevalence of osteoplastic pulmonopathy, which in workers of dust professions may occur under the guise of lung calcification, being, in fact, a form of pneumoconiosis.https://mednauki.ru/index.php/MK/article/view/1173остеопластическая пульмопатияпневмокониозшахтерыэпителиально-мезенхимальная трансформацияостеогенез в легкихугольно-породная пыльклеточные механизмы фиброзафакторы остеогенеза |
| spellingShingle | Олег Иванович Бондарев Мария Сергеевна Бугаева Евгения Викторовна Уланова PHENOTYPIC PLASTICITY OF BRONCHOPULMONARY EPITHELIUM IN THE DEVELOPMENT OF PULMONARY OSSIFICATION IN MINERS (ANALYTICAL REVIEW, ANALYSIS OF CLINICAL CASES, SUBSTANTIATION OF THE RESEARCH METHOD) Медицина в Кузбассе остеопластическая пульмопатия пневмокониоз шахтеры эпителиально-мезенхимальная трансформация остеогенез в легких угольно-породная пыль клеточные механизмы фиброза факторы остеогенеза |
| title | PHENOTYPIC PLASTICITY OF BRONCHOPULMONARY EPITHELIUM IN THE DEVELOPMENT OF PULMONARY OSSIFICATION IN MINERS (ANALYTICAL REVIEW, ANALYSIS OF CLINICAL CASES, SUBSTANTIATION OF THE RESEARCH METHOD) |
| title_full | PHENOTYPIC PLASTICITY OF BRONCHOPULMONARY EPITHELIUM IN THE DEVELOPMENT OF PULMONARY OSSIFICATION IN MINERS (ANALYTICAL REVIEW, ANALYSIS OF CLINICAL CASES, SUBSTANTIATION OF THE RESEARCH METHOD) |
| title_fullStr | PHENOTYPIC PLASTICITY OF BRONCHOPULMONARY EPITHELIUM IN THE DEVELOPMENT OF PULMONARY OSSIFICATION IN MINERS (ANALYTICAL REVIEW, ANALYSIS OF CLINICAL CASES, SUBSTANTIATION OF THE RESEARCH METHOD) |
| title_full_unstemmed | PHENOTYPIC PLASTICITY OF BRONCHOPULMONARY EPITHELIUM IN THE DEVELOPMENT OF PULMONARY OSSIFICATION IN MINERS (ANALYTICAL REVIEW, ANALYSIS OF CLINICAL CASES, SUBSTANTIATION OF THE RESEARCH METHOD) |
| title_short | PHENOTYPIC PLASTICITY OF BRONCHOPULMONARY EPITHELIUM IN THE DEVELOPMENT OF PULMONARY OSSIFICATION IN MINERS (ANALYTICAL REVIEW, ANALYSIS OF CLINICAL CASES, SUBSTANTIATION OF THE RESEARCH METHOD) |
| title_sort | phenotypic plasticity of bronchopulmonary epithelium in the development of pulmonary ossification in miners analytical review analysis of clinical cases substantiation of the research method |
| topic | остеопластическая пульмопатия пневмокониоз шахтеры эпителиально-мезенхимальная трансформация остеогенез в легких угольно-породная пыль клеточные механизмы фиброза факторы остеогенеза |
| url | https://mednauki.ru/index.php/MK/article/view/1173 |
| work_keys_str_mv | AT olegivanovičbondarev phenotypicplasticityofbronchopulmonaryepitheliuminthedevelopmentofpulmonaryossificationinminersanalyticalreviewanalysisofclinicalcasessubstantiationoftheresearchmethod AT mariâsergeevnabugaeva phenotypicplasticityofbronchopulmonaryepitheliuminthedevelopmentofpulmonaryossificationinminersanalyticalreviewanalysisofclinicalcasessubstantiationoftheresearchmethod AT evgeniâviktorovnaulanova phenotypicplasticityofbronchopulmonaryepitheliuminthedevelopmentofpulmonaryossificationinminersanalyticalreviewanalysisofclinicalcasessubstantiationoftheresearchmethod |