Lactylation modification in cancer: mechanisms, functions, and therapeutic strategies
Abstract Cancer remains the leading cause of mortality worldwide, and the emergence of drug resistance has made the identification of new therapeutic targets imperative. Lactate, traditionally viewed as a byproduct of glycolysis with limited ATP-producing capacity, has recently gained recognition as...
Saved in:
| Main Authors: | Mengqi Lv, Yefei Huang, Yansu Chen, Kun Ding |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2025-03-01
|
| Series: | Experimental Hematology & Oncology |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s40164-025-00622-x |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Lactylation: From Molecular Insights to Disease Relevance
by: Yao Xu, et al.
Published: (2025-06-01) -
Lactylation-mediated miRNA regulation in cancer therapy resistance
by: Yiyi Shou, et al.
Published: (2025-08-01) -
Nonhistone lactylation: A hub for tumour metabolic reprogramming and epigenetic regulation
by: Dawei Zhang, et al.
Published: (2025-08-01) -
Lactate and lactylation: emerging roles in autoimmune diseases and metabolic reprogramming
by: Wenjun Liu, et al.
Published: (2025-06-01) -
Metabolic reprogramming promotes apoptosis resistance in acute lymphoblastic leukemia through CASP3 lactylation
by: Zhi Lin, et al.
Published: (2025-07-01)