Lactylation modification in cancer: mechanisms, functions, and therapeutic strategies

Abstract Cancer remains the leading cause of mortality worldwide, and the emergence of drug resistance has made the identification of new therapeutic targets imperative. Lactate, traditionally viewed as a byproduct of glycolysis with limited ATP-producing capacity, has recently gained recognition as...

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Bibliographic Details
Main Authors: Mengqi Lv, Yefei Huang, Yansu Chen, Kun Ding
Format: Article
Language:English
Published: BMC 2025-03-01
Series:Experimental Hematology & Oncology
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Online Access:https://doi.org/10.1186/s40164-025-00622-x
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